In this study, statistical differences by sex in all parameters evaluated were not observed, however, the median serum OPN concentration showed a trend (p = 0.107) towards an increment in boys (70.05 ng/mg of total protein) compared to girls (30.33 ng/mg of total protein).
However, the T-αFGL2 cells showed a trend toward enrichment in core T RM genes when compared with T-Ctr cells (Supplementary Fig. 8f , NES = 1.23, P = 0.107), suggesting that T-αFGL2 treatment does not directly transform regular T cells into brain tumor–specific T RM cells.
Perfusate potassium levels showed a trend towards an increase in the banked blood group (5.4 versus 7.6 mmol/L; P = 0.107); there were no differences in sodium (142.0 versus 143.9 mmol/L; P = 0.404) and bicarbonate (13.0 versus 14.3 mmol/L; P = 0.491) concentrations.
Carrier children showed a trend ( p = 0.107, two-tailed Mann-Whitney test) towards carrying a higher number of minor eQTLs alleles (average = 4.3/person) than their carrier parents (average = 3.2/person) (Additional file 1 : Fig.
Analysis of overall survival (OS) showed a trend towards shorter OS in the HR patient cohort (HR vs LR days, p = .107; Supplementary Fig.
Of note, glioblastoma individuals with SAO without surgery delay showed a trend to longer OS than the above-mentioned 14 cases with delayed surgery after SAO (13.0 vs 7.7 months, P = .1073).
HR for all cardiac events showed a trend in women with an HR of 1.021 (per 1‐ms increment in SD‐TPS, P =0.108) but no relation in men ( P =0.191).
Unadjusted revision-free survival showed a trend favoring osteoarthritis compared to osteonecrosis (Fig. 1 ; p = 0.108).
Assay trees at a 7‐m distance showed a trend (Table 2 ; p = .1080).
These 9 negative results showed a trend toward longer time from symptom onset compared to the 29 rt-PCR assay–positive/antigen test–positive specimens (average, 4.4 vs 2.9 days, P = .108) [ 16 ].
The comparative analysis of foetal survival curves between infected groups showed a trend towards statistical significance ( P = 0.108) with a higher foetal median survival time in G2.
Achieving pCR was associated with improved DFS, with a statistically significant difference in DFS curves between PCR and nonPCR cases ( p =0.008) ( Figure 2A ), and PCR patients also showed a trend toward better OS, but not statistically different ( p =0.108) ( Figure 3A ).
Hypomethylating agents are the most frequently used agents in the therapy of elderly AML in the US and Europe.[ 12 ] The DACO-016 study compared the efficacy and safety of decitabine (20 mg/m 2 /day for 5 days every 4-week) versus investigators choice (including LDAC 20 mg/m 2 /day for 10 days every 4-week or best supportive care) in 485 AML patients (median age 73 years) ineligible for cytotoxic chemotherapy.[ 12 , 13 ] The initial analysis showed a trend toward improved survival with decitabine (7.7 vs. 5.0 months; P = 0.108) that became significant ( P = 0.037) with further follow-up.
When adjusted by tumor size, NLR ≥ 2.49 just showed a trend to decrease CR rate (adjusted OR = 1.547; 95% CI, 0.909–2.631; P = 0.108).
In addition, 26% of patients in this study underwent reduced intensity conditioning (RIC) allogeneic stem cell transplantation, and they showed a trend of longer event-free survival and less transplant-related mortality in univariate analysis ( P = .108 and .107 resp.).
In further exploring its relevance to the clinical diagnoses of dementia, Fisher’s exact tests revealed that clusters have a statistically significant association with the Braak staging of dementia ( P = 0.0025) and showed a trend of association with diagnoses of dementia by the NINCDS-ADRDA Alzheimer’s criteria ( P = 0.108), one of the most widely used criteria in the diagnosis of Alzheimer’s disease.
The effect of BR297 (2.5 mg/kg) showed a trend to lower potency in the early SI mice [+235%, t (26) = 1.66, p = 0.108].
After a median follow up duration of nine months, this study showed a trend for improved PFS (HR, 0.86; 97.58% CI: 0.69–1.06, P = 0.108) and OS (HR, 0.86; 97.54% CI: 0.65–1.13; P = 0.219); however, these results were not statistically significant.
Overexpression of the PI3K/AKT/MTOR signature showed a trend toward improved response to everolimus (interaction P = 0.1085).
Although the AZA group showed a trend toward prolonged median OS (10.4 vs. 6.5 months; HR 0.85, P = 0.1087) without reaching the threshold for statistical significance, Europe and Japan granted approval based on survival benefits observed in sensitivity and domestic analyses [ 44 ].
This was not due to alterations in food intake as while SFN showed a trend towards decreasing food intake in C57BL/10 mice ( p = 0.1087), it had no impact on food intake in mdx mice ( Figure S2 ).
Effects of PTZ treatment on mRNA expression of epilepsy-related genes in the hippocampus, neocortex and prefrontal cortex PTZ treatment significantly upregulated Fos mRNA expression in neocortex ( P = 0.0001) and prefrontal cortex ( P = 0.0003; Table 1 ) whilst hippocampal Fos mRNA expression only showed a trend to increase ( P = 0.1089).
Finally, NLR showed a trend toward association with cfDNA levels (Fig. 5 C) ( r = 0.2360, p = 0.1089 ).
In the results of this study, although no statistical differences were shown, workers with single exposure to noise still showed a trend toward an increased risk of developing hypertension (OR, 1.79; 95% CI, 0.88–3.65; P = 0.109) after adjusting for age, sex, and BMI in model 3, which are confounding factors that may affect the results.
Nevertheless, comparison between the preoperative impedance and the one measured after the 3rd stimulation week showed a trend towards increased values for the uncoated group (p = 0.109), while for the coated electrodes almost no difference was found (all p values >0.800).