showed a trendp < 0.200
On the other hand, rs4714384 CT showed a trend toward association ( p < 0.200) but did not reach significance levels.
On the other hand, rs4714384 CT showed a trend toward association ( p < 0.200) but did not reach significance levels.
Using a median cutoff of 4 cells/mm 2 to detect B cell–infiltrated tumors ( 21 ), we showed a trend toward improved OS in CD20 + -infiltrated tumors pre-NACT (median survival: 37.7 vs. 47.1 months; low vs. high B-cell infiltrated; P = 0.2 log-rank test).
Firstly, in the exploratory MARS cohort 4 out of the 16 candidate genes (from 18 features), showed significantly different expressions ( p ≤ 0.05) between the response groups at least under one of the incubation conditions: glutamate decarboxylase 1 ( GAD1 ), FYN binding protein ( FYB ), receptor activity modifying protein 1 ( RAMP1 ), TBC1 domain family member 9 ( TBC1D9 ), while other four genes showed a trend ( p ≤ 0.2): paired like homeodomain 1 ( PITX1 ), nuclear factor I B ( NFIB ), glutamate ionotropic receptor NMDA type subunit 2A ( GRIN2A ), aminoadipate aminotransferase ( AADAT ) (Fig. 2b, c , Supplementary Table 8 ).
Under conditions of endotoxemia, the levels of membrane-bound Gal3 statistically decreased in all the immune cell subsets with the exception of CD8 + T-cells, CD4 + T-cells, and DCs, which only showed a trend ( p = 0.2, p = 0.056 and p = 0.056, respectively) to a reduction of levels of Gal3 after the LPS exposure ( Figure 2 ).
The reported events were fewer in the canagliflozin studies, and the treatment effect showed a trend towards a reduction of SAE AKIs (OR 0.72 [95% CI 0.43–1.20], p = 0.20).
While CDKN2A loss showed a trend towards shorter PFS (4.9 vs. 9.7 months; p = 0.2), CDKN2B loss was significantly associated with worse outcomes (PFS 4.8 vs. 11.0 months; p = 0.03).
Other variables that showed a trend (i.e., p <0.20) included age (higher age was associated with greater anxiety), educational level (persons with college education had greater anxiety than those with elementary education), female gender (women were more anxious than men), and the presence of medical complications (those with complications had less severe anxiety).
However, the DCM group showed a trend toward decreased CD4 + naive T cells compared with UVF (median 41%, IQR 26–54 vs. 44%, IQR 30–53, P = 0.2 by Mann-Whitney U test, Figure 1A ).
In stark contrast, the PL group showed a trend toward shorter OS (HR 1.35, 95% CI 0.81–2.25, P = 0.2, Log-rank test) and PFS (HR 1.23, 95% CI 0.79–1.92, P = 0.4, Log-rank test) (Fig. 2a ) in PD-L1 ≥ 1% versus PD-L1 < 1% tumors.
Educational level showed a trend toward an association (p = 0.20).
Comparing the interval from PrTu diagnosis to LiMe between the high and low miRNA-21 expression group showed a trend towards faster development of LiMe (p = 0.20; Fig 2b ) with higher miRNA-21 levels in the PrTu.
Flow cytometry at day two post-MI showed a trend towards increased myocardial homing of CD45 + /CD34 + mononuclear cells (1.1 ± 0.3% vs. 0.7 ± 0.1%, p = 0.2).
Although pseudoislets showed a trend of reduction in first/second phase SI (mean ± SD = 1.73 ± 0.6) compared with fresh islets ( P = 0.20), the ratio was higher compared with cultured‐intact islets ( P < 0.05, Fig. 2 C).
There was one significant correlation between Aβ AI and cognitive test results in the AD-MCI-Aβ + group, namely for Aβ AI and Digit span – Backwards ( Tau = 0.68, p = 0.03), but no other correlations showed a trend towards significance ( p > 0.2).
The ARNI group showed a trend toward higher left ventricular ejection fraction (LVEF: 37.3±3.9% vs. 46.8±6.5%, P=0.20), lower plasma BNP levels (238.1±73.6 vs. 184.6±55.8 pg/mL, P=0.60), lower creatinine levels (1.60±0.20 vs. 1.38±0.17 mg/dL, P=0.45), and higher estimated glomerular filtration rate (34.0±4.9 vs. 39.6±3.9 mL/min/1.73 m 2 , P=0.27) than the non-ARNI group.
Comparison with other incidence data Sero-incidence and incidence of reported cases showed a trend towards an inverse correlation (Spearman’s rho = −0.5, p = 0.2; Figure 2 ).
We considered parameters that showed a trend (with P < 0.2) toward affecting ovarian parameters in the subsequent multivariate logistic regression model.
Morning treatment ( n = 158) showed a trend toward improved overall survival vs. afternoon ( n = 79); the median survival was 158 vs. 79 days ( p = 0.20, HR = 0.84, CI 95% 0.84–0.91).
Several independent variables showed a trend of association ( P < 0.2) in the Spearman rank analysis.
Although all markers showed a trend for association with survival (Training p<0.20), stromal TEM-1 expression as well as stromal vessel Col I and HIF2α were the only biomarkers to validate in the univariate setting.
Starting with all variables that showed a trend towards an association ( p < 0.2), a best subset regression procedure was used to identify the most suitable and parsimonious multivariate model, defined as the one with the lowest Akaike Information Criterion (AIC), a widely recognized measure of model fit [ 43 ].
All variables that showed a trend towards an association ( P < 0.2) were included in the logistic regression analysis.
Children so compared showed a trend to more prevalent wheeze (OR: 1.21, 95% CI: 0.90–1.62, p = 0.20) and current asthma (OR: 1.27, 95% CI: 0.99–1.63, p = 0.06).
Only factors that appeared to have a significant impact on the risk for complications in UC or which showed a trend with p < 0.2 in the univariate analysis were included in the multivariate analysis.
In addition, the US group showed a trend of progression over 2 years in maximum carotid wall thickness (4.4% vs. -1.3%, p=0.2) and percent wall volume (0.08% vs. -0.5%, p=0.057) compared to regression in the AS group. 4.