Barely Significant
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showed a trend

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Subjects with MCI (CDR 0.5, n = 20) showed a trend toward higher levels than controls (CDR 0, n = 18), but the trend did not reach statistical significance. p3-Alc α levels in subjects with mild AD (CDR 1, n = 13) were significantly higher than those in controls ( p < 0.05; Tukey-Kramer’s multiple comparison test).
showed a trendP = 0.051.0× alpha
Although the mean median pitch remained within normal range with an overall non-significant change (−3.8, NS), analysis by gender showed a trend for statistical significance ( P = 0.05) on the impact on median pitch (i.e. the fundamental frequency): while it decreased among 80% of the female patients [from 203 ± 38 to 189 ± 31 Hz (normal range: 140–220 Hz), n = 19], it was almost unchanged in the male patients [from 135.2 ± 23 to 134.5 ± 26 Hz (normal range: 85–180 Hz), n = 29] ( Supplementary Fig. 1 ).
showed a trendP > 0.051.0× alpha
Our results failed to show significant differences in IL-7 induced Bcl-2 expression among the different groups, although, Ag stimulation of the PBMCs of the oldest donors showed a trend to a reduced expression of this molecule (from 0.11% ± 0.03 to 0.08% ± 0.02), which did not achieve statistical significance ( P > 0.05) in comparison with those from the youngest individuals (data not shown).
showed a trendp > 0.051.0× alpha
With the increase of selenium concentration, the content ratio of acetic acid to propionic acid in rumen fluid of sika deer at the velvet antler growing stage increased at first, before decreasing and then increasing again, among which the content ratio of SY3 acetic acid to propionic acid was the lowest ( p > 0.05), while the content of butyric acid in rumen fluid showed a trend of increasing at first and then decreasing, and the content of butyric acid was the highest in SY3 ( p > 0.05).
did not reach statistical significancep>0.051.0× alphaplainly factual
showed a trendp>0.051.0× alpha
It is worth noting that although the box plots of some genes (such as PDGFD) showed a trend of differences between groups, these differences did not reach statistical significance (p>0.05), possibly due to the limitation of sample size (only 29 samples in each group) and the high variability (standard deviation >50%) of IC50 values for some drugs.
showed a trendp = 0.051.0× alpha
Planned contrasts revealed that participants with depression were significantly less accurate in identifying happy faces than controls, t(86) = − 2.39, p = 0.005, η 2 = 0.25, but participants with GAD were not significantly different from controls although they showed a trend in the same direction, t(86) = − 1.68, p = 0.05, η 2 = 0.18 ( Fig. 1 a).