Meanwhile, the Anti-CTLA4 group showed a trend of rapid tumor growth after eight days of treatment, indicating that the therapeutic effect of Anti-CTLA4 alone was not satisfactory ( P > 0.05), while the combination treatment with X-PDT or RT could achieve better tumor suppression effect due to the immune system activation by X-PDT.
Kaplan-Meier analysis also showed a trend of improved survival in mice treated with pevonedistat alone and in combination over the control group (p < 0.05) (Figure 6C ).
Neither UIC nor SSC sample replicated the findings of the Silverman study; however, the SSC sample showed a trend toward more severe 'overall level of language' score (p < 0.05) in the G/G genotype groups of both rs2056202 and rs2292813.
Nuclear NANOG expression showed a trend to associate with a higher grade of dysplasia (Fisher’s exact test p = 0.05) ( Table 1 ). 3.3.
While changes in total protein concentrations were less pronounced ( Figure 4 B), rhesus in particular showed a trend towards decreasing total protein concentrations, with greater decreases than those of cynos or AGMs throughout the disease course (p<0.05).
In this initial trial, young adult neurabin KO mice showed a trend toward reduced immobility compared with matched WT mice ( p = 0.05, Fig 3A ).
ADAMTS 13 activity, showed a trend towards lower levels in moderate and severe COVID-19 patients compared with control, but did not reach the conventional p < 0.05 value of statistical significance ( Fig. 1 C).
We defined TMB > 12 (mutations/Mb) as high TMB group in consistent with our previous report, which showed a trend of better mPFS than low TMB group [HR, 0.450; CI, (0.196–1.034); p > 0.05].
Interestingly, similar to propensity matched score results, HFpEF showed a trend of lower 1-year mortality risk (OR 0.6, p=0.05).
Jonckheere–Terpstra trend test showed a trend of MAP and DBP to increase with increasing PWV ( p < 0.05).
In addition, they showed a trend effect for up-regulation of genes implicated in GABA synthesis: GLS (p = 0.050) and GAD1 (p = 0.050) and significant down-regulation of ABAT (p = 0.030) that plays a role in GABA metabolism.
Among the regions considered, only the right TPJ (associated with mentalizing on action goals) showed a trend towards significant activation (p<0.05 uncorrected) while observing both cooperative and affective pictures.
Parietal alpha showed a trend-level correlation ( r = 0.288, p = 0.050 for right parietal).
Reference men with b2/b4 duplication compared to subjects with no AZFc rearrangements showed a trend for lower follicle-stimulating hormone (FSH) (median 2.3 [5–95% range 1.4–7.5] vs 3.2 [1.3–7.1] IU/l; p<0.05) and luteinizing hormone (LH) (3.1 [1.7–5.0] vs 3.8 (1.7–7.2) IU/l; p<0.05).
The α-diversity and NMDS analysis of bacterial community The shannon index and richness index of the total bacterial community increased ( Fig 2A , P < 0.05) with distance from the mining area and reached a maximum at distance H5, while the simpson index showed a trend of increasing and then decreasing, and then reached a maximum at distance H2 (P < 0.05), and was higher than that of H0, although it decreased at distances H3 and H5.
Among the demographic characteristics included in the final multivariable logistic regression model, only the age of psoriasis onset showed a trend towards a higher odds of having PsA ( p = 0.050).
Quantitative difference in GCSF-, MCP-1-, TPO- or IL-6-expression showed a trend towards a change in values, however did not reach statistical significance. hCG levels, were significantly decreased in patients with miscarriage compared to those with ongoing pregnancy (151.75 ± 25.29 IU/l vs. 351.27 ± 111.02 IU/l, p < 0.05) However, they were within normal limits and therefore not predictive for pregnancy outcome.
Although RMT also showed a trend toward improved quality of life (SMD 1.00, 95% CI 0.00-1.99; P = .05), this result was borderline significant and derived from only three studies and should therefore be interpreted cautiously.
The baseline mYPAS showed a trend toward lower anxiety in the combined No-PP-Script groups of 23.3 (23.3–28.3) vs the combined PP-Script group (23.3 [23.3–33.3]; p=0.05).
Anxiety scores (HADS-Anxiety) showed a trend toward improvement in the intervention group, reaching borderline significance at T48 ( p = 0.05).
MiR-21 showed a trend of upregulation (>1.6-fold, p<0.05) only at 12 h post-OGD.
Swing and stance time differences were only significant between 60 and 66 years ( p < 0.001) and showed a trend to reach significance ( p =0.05) in the 67 to 75 years group, which could be associated with the sample size increasing type 2 error.
These seven SNPs showed a trend towards association with ADHD in the case-control GWAS (p<0.05).
ruthenicum roughage addition to the diet ( Figure 3B ); the relative abundance of the NK4A214_group showed a trend of increasing and then decreasing ( p < 0.05) with increasing levels of L. ruthenicum branches additions in the diet ( Figure 3C ); and the relative abundance of sheep ruminal microbiota phylum level species among groups had no significant effect ( p > 0.05) ( Figure 3A ).
The requirement for a dental review showed a trend towards a longer time from referral to treatment initiation ( p > 0.05, Figure 2 b).