Barely Significant
← all phrases

“showed a trend”

53,323 sentences · 53,323 papers · 65,371 search hits before verification

In the literature

In this study, roflumilast showed a trend toward reducing exacerbation rates in patients. 18 Two Phase III, 6-month, randomized, double-blind, placebo-controlled, multicenter trials assessed the benefit of adding roflumilast to long-acting bronchodilators in patients with moderate-to-severe COPD. 29 In the first study, 933 patients were randomized to receive roflumilast 500 μg plus salmeterol (long-acting beta agonist [LABA]) or placebo plus salmeterol, while 743 patients in the second study were randomized to receive roflumilast 500 μg plus tiotropium or placebo plus tiotropium.
failed to reach statistical significanceP =0.1893.8× alphaplainly factualgold
When IMAs were divided into MICA and MOCA subgroups and compared with the mucus-negative group, survival data showed a trend of difference between the three groups, but the results failed to reach statistical significance (RFS: MICA versus mucus-negative, log-rank P =0.189; RFS: MOCA versus mucus-negative, log-rank P =0.648; OS: MICA versus mucus-negative, log-rank P =0.312; OS: MOCA versus mucus-negative, log-rank P =0.106; Figure 2C and D ).
Univariate and multivariate survival analysis showed a trend towards decreased hazard of MS with increasing 25HVITD levels albeit insignificant (HR: 0.987 [0.968;1.006], p:0.202 and HR: 0.988 [0.969;1.007], p:0.217 respectively).
30 31 33 54 64 They showed a trend towards a greater risk of menstrual problems with FGM/C: dysmenorrhoea (RR=1.44, 95% CI 1.11 to 1.86), difficulty in menstruation (RR=1.02, 95% CI 0.06 to 16.28), menstrual problems (RR=0.77, 95% CI 0.61 to 0.97), irregular menses (RR=2.56, 95% CI 1.48 to 3.45) and difficulty in passing menstrual blood (RR=1.75, 95% CI 0.78 to 3.93).
A meta-analysis of nine observational studies (6 cohort, and 3 case-control), however, showed a trend but not a significant association between metformin and the risk of developing pancreatic cancer [48] , indicating a significant heterogeneity in clinical studies on the relationship between metformin use and pancreatic cancer risk.
The randomly generated gene list showed no significant over-representation of GWAS genes in the random gene set; in fact, it showed a trend of under-representation of GWAS genes in the random HOMER gene set, primarily due to the fact that some gene names in the NHGRI GWAS catalog are not RefSeq annotations (online supplementary table S13).