We found increasing maternal vitamin D concentration showed a trend towards a reduced risk of preterm delivery.
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Although not significant, antigen-specific cytokine levels showed a trend to a decrease of IL-4 production by CD1d −/− LN cells than wild type counterparts and to an increase of IL-4 production in the C57BL/6 mice which had received αGalCer analog PBS57 ( Figure 3G ).
Vaccinated animals (range 2.2% to 5%) showed a trend towards slightly less weight loss and more rapid recovery compared to naïve ferrets (range 3.3% to 8%), but this did not reach statistical significance.
Kidney function tests performed on serum from the same group of mice showed a trend for elevation of BUN in knockout mice but this did not achieve statistical significance (Table 2 ).
Studies in the 1980s showed a trend towards an increase among adult Saudis especially females.[ 5 ] A large study of Saudi patients from 1995 to 2000 revealed prevalence of 23.7%.[ 6 ] However, a study in 2011 showed a significant rise in prevalence reaching 34.1% in men and 27.6% in women.[ 7 ] Correct knowledge about diabetes and its management has an enormous impact on attitude and practice of diabetic patients.
qPCR data showed a trend for reduced expression of CCL5, CCl2 and IL33 in Nod2 −/− CEC post-infection although this was not significant ( Figure 7E-G ).
Conclusions Taken together, our observations suggest that curcumin may be beneficial to attenuate exercise-induced DOMS, and larger studies could provide statistical significance also for the functional and biochemical parameters that only showed a trend to improvement in our study, like the histological evaluation of muscle damage.
Miners and colleagues previously showed a trend of divergence between ACE levels and activity in postmortem CSF, but this was not significant and the patterns observed may have been an artifact of postmortem delay where additional changes to the ACE may have occurred post mortem [ 22 ].
No significant differences were observed with differing anticoagulants, although the observed concentrations of NGAL in the ultrafiltrate of those treated with citrate showed a trend toward lower concentrations which may reflect less generated NGAL from sequestered inflammatory cells.
DISCUSSION The main findings of this study are that: 1) successful RFCA in patients with paroxysmal AF decreased LAVmax and function in the short-term and showed a trend of recovery of LA function in the long term, whereas the patients with recurrence of AF had worse LA function; 2) patients with recurrent AF had significantly larger LA volumes than patients without recurrent AF; and 3) the LAVmax RFCA was an independent predictor of AF recurrence after ablation.
Rituximab decreased the recurrence rate and showed a trend in favour of improvement in overall survival or disease-free survival [ 22 ].
In comparison with nonsmokers, former smokers (31.1%) showed a trend toward TST1 positivity (cut-off indurations of 5 mm and 10 mm).
Conclusions Local over-expression of VEGF-D ΔNΔC in the UtAs of pregnant mid-gestation sheep reduced vasoconstriction, promoted endothelial cell proliferation and showed a trend towards increased UABF.
In Saos-2 cells, the osteogenic cell differentiation, measured by the expression of osteocalcin and collagen I, showed a trend opposite to the trend for cell proliferation.
30% via epoetin administration in patients with congestive heart failure or ischemic heart disease undergoing dialysis showed a trend towards increased mortality and myocardial infarctions, [21] so there potentially could be some risk in using higher targets in this population.
Although the remaining genes were not statistically significant at P < 0.05, they showed a trend towards differences between the two groups.
In contrast to our finding, in the study of Kaka et al ., adding rifampin to cotrimoxazole showed a trend toward antagonism in vitro ;[ 16 ] also, in the study of Harvey et al ., the rifampin-trimethoprim-sulfamethoxazole combination was antagonistic in vitro against S. aureus .[ 17 ] Therefore, the efficacy of such antibiotic combinations should be evaluated in clinical trials.
On univariate analysis, total tumor volume ≥3 cc ( P = 0.02) was associated with worsened overall survival and male gender ( P = 0.07) showed a trend suggesting association.
Koreans showed a trend toward less use of available information sources, particularly less use of printed materials in drug information seeking.
fragilis (false discovery rate (FDR)<5%), and showed a trend (FDR<20%) towards positive association with Dialister spp. and a negative association with the Prevotella group ( Supplementary Table 4 ).
The frequency of repair events utilizing microhomology increased significantly in the heart and lung fibroblasts and showed a trend towards increase in the astrocytes with age ( Figure 4B ).
Plasma levels of hs-CRP and ET-1 showed a trend to increase that led to a significant difference between tertile subgroups. hs-CRP and ET-1 values reached statistical significance between Ca × P product tertiles (ANOVA; P < 0.0001, P < 0.0001, respectively).
In contrast at 100 μM only the phenylalanine-tyrosine combination showed a trend of down-regulation (Fig. 3 c).
Median OS was not reached for the abiraterone group in the final analysis; the OS was 27.2 months for the placebo group and there was a 25% decrease in the risk of death in the abiraterone group, which showed a trend toward OS improvement.
Previously reported that colorectal cancer patients with higher TAZ expression showed a trend of shorter survival times [ 42 ].