[ 15 ] found that the overall incidence of PONV during the 24 h after surgery showed a trend toward a lower incidence in the dexmedetomidine group, but it did not reach statistical significance.
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When the samples were grouped on the basis of dietary habits, the PLS-DA models showed a trend of differentiation according to the geographical origin of the samples in the omnivore and vegan subjects (at least for Bari, Parma and Bologna), while the samples from Torino were only clearly separated in the case of the ovo-lacto-vegetarian population ( Fig 5 ).
The oral CEE group also showed a trend in improvement on measures of anger-hostility and memory recall of printed material. 21 Ultimately, the recent results of the KEEPS and the KEEPS Cog study are that if there proves to be a window of time in the early post menopause when initiation of long-term HT has a net beneficial effect, then women can feel reassured that treatment of their menopausal symptoms when they are likely to be the most severe, can concurrently protect their vascular system, reduce bone reabsorption, or even elicit neuroprotection from dementia in late life. 21 , 22 4.
Notably, Mapt −/− neurons also showed a trend toward reduced A5 positivity compared to Mapt +/+ neurons.
Gold et al 4 reported SFTs greater than 10 cm had a statistically significant worse outcome for metastasis and also showed a trend toward an increased local recurrence disease survival.
In this study, high FOXA1-expressing tumours showed a trend towards being associated with better outcomes, although it was not statistically significant, corresponding to the results of previous studies.
As the authors note, IVC induction showed a trend to improved efficacy and reduced TF in the ALMS maintenance study. 5 Unfortunately, the relative role of the maintenance agents are not assessed.
In a randomized phase 2 trial of rilotumumab±epirubicin/cisplatin/capecitabine in gastric or oesophagogastric junction cancer, patients receiving rilotumumab showed a trend towards improved survival, especially in MET-positive patients, but no clear dose–response relationship was observed.
We further confirmed this data at 2 and 6 h and showed that Cort and NE showed a trend towards an increase in p21, and these levels were reduced in cells pre-treated with RU-486 and propranolol, respectively.
The oxidized fraction of GSH (glutathione disulfide, GSSG) showed a trend toward an increase in the aging myocardium ( Figure 4e , left panel).
HbA1c levels showed a trend toward reduction (− 0.06%) in MS, and was significantly declined by − 0.43% (95% CI − 0.55 to − 0.31%, p = 0.009) in T2DM.
Evidence bases for this recommendation are the studies VISEP, CRYSTMAS, 6S, and CHEST [ 2 – 5 ], which showed a trend in the HES groups [ 2 , 3 , 5 ] or significance [ 4 ] for higher mortality and the need to employ renal replacement therapy significantly more frequently.
Though studies have reported that high beta tubulin expression predicted resistance to vinorelbine [ 51 ], no improvement in survival was seen in patients assigned to either chemotherapy or observation in the low tubulin group, whereas in the high tubulin group, patients who received chemotherapy showed a trend towards overall improved survival, and hence, a significant treatment based on tubulin interaction could not be shown [ 50 ]. 2.8.
However, after knocking down of ILK, EE still showed a trend of enhanced memory, which suggested that ILK might not be the sole factor to mediate the functions of EE.
Quercetin, an average inhibitor of both pathways, showed a trend towards increasing NAD + levels to normal.
Overexpression of irs2 and btr01 protects against acute hypoxic stress in the absence of preconditioning During MO knockdown and rescue experiments, we noted that btr01 morphants injected with rescue btr01 mRNA showed a trend toward lower lethality when subjected to sH in the absence of hPC ( Figure 5B ).
Changes in Ki-67 scores between T1 and TS showed a trend toward association with RFS, but did not reach significance ( P = 0.075 by LR test).
Of note, testicular type I TE also showed a trend towards hypomethylation in ICR_M (only 18 probes).
Bd -tolerant populations showed a trend toward higher heterozygosity ( H O ) and allelic richness (AR; Fig. 2A , B ), and Bd -uninfected populations had the lowest measures of H O and AR (Fig. 2C , D ).
The effect on IL-6 production showed a trend towards a reduction.
The incidence of diabetes mellitus also showed a trend towards being higher in the NICOM group.
Response rates at 3 months (64 % versus 35 %; P = 0.069) and 6 months (78 % versus 40 %; P = 0.064) showed a trend in favour of glass microspheres, but survival showed no difference (heavily biased by HCC).
However, PIK3CA mutation showed a trend toward a significant adverse effect on OS with a pooled HR of 1.83 (95% CI, 1.05-3.20) in NSCLC patients treated with EGFR-TKIs ( Figure 5C ).
When ifferentiated into the different sample areas, all the litter materials showed a trend to having the highest moisture values in the drinking areas.
The gene expression of 11 β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) showed a trend to lower values in the LPS group.