None of these genes exhibited significant differences in PFI, but it was observed that the P value was the smallest and showed a trend towards statistical significance.
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In the literature
In most of the trials discussed above, patients with higher PD-L1 expression showed a trend toward better survival following treatment with immune checkpoint inhibitors.
Our results showed a trend toward impairments in context recall in only male eNOS KO mice.
The study showed a trend of improving female education, because all the 35 participants had some form of formal education.
Before health education, the health literacy level of residents' hepatitis B prevention and control basically showed a trend of decline with the increase of age, and the health literacy level was the highest in the age group of 35 ~ years old, and the lowest in the age group of 55 + years old.
According to existing clinical data, we also found that although the overall clinical prognosis showed a trend of improvement after IL‐2 intervention in both clusters of patients, the difference in prognostic benefits was significant only after 1 week of IL‐2 intervention between the clusters.
At P14, no differences were found between normoxia- and hyperoxia-exposed mice; however, the brain regions of hyperoxia-exposed mice showed a trend of becoming progressively hyperoxic as the mice aged ( Supplemental Figure 3 , A–C).
3 c,d, COD removal of the landfill leachate showed a trend of first increasing and then decreasing along with the increment of SnO 2 nanoparticles amount.
At final follow-up, sagittal tilt showed a trend to being slightly increased compared with that after the 2nd operation.
During the overwintering period in 2021, the changes in the proline content of BLF treatment were similar to those in 2020, which also showed a trend of first increasing and then decreasing, while the proline content of CK was basically stable ( Figure 6D ).
This result showed a trend similar to that of the PCA plot of the microbial community.
Finally, PAH showed a trend of having lower RM and RIx compared to NP and HP, with no differences between GH and PE.
In unpublished observations, we found in patients with severe obesity that jejunal SMVT expression showed a trend of negative correlation with the expression of TNF-alpha by CD4 +lymphocytes and MAIT cells, a T cell subset known to be activated by gut microbial activity. 41 Thus, the combination of increased intestinal inflammatory tone, together with the lowered number of biotin-producing bacteria, might be detrimental for the host biotin availability.
CCL3, CCL4, CCL17, CXCL1, and CXCL5 levels showed a trend to increase among CRLM-derived cultures ( Figure 10 B ).
Of the three studies independently comparing RAILE and VAILE, one reported significantly higher LN yield conducted by RAILE ( 33 ), one showed a trend in favor of RAILE ( 35 ), and one reported no significant difference ( 36 ), suggesting better or similar LN yield in RAILE.
Also, they showed a trend toward using retro pupillary iris-claw IOL more frequently at the time of the primary surgery.
RANKL secretion was significantly higher at day 7 on stiffer hydrogels while its decoy receptor OPG showed a trend towards an increase at day 7 on stiffer hydrogels ( Figures 5C,D ).
With an increasing duration of heat stress, the protein expression level of Nrf2 in the HS group showed a downward trend, while HO-1 showed a trend of first increasing and then decreasing.
6 ) showed a trend whereby the cytotoxicity in human cells increases with time of exposition of cells to our 2D nanomaterials samples.
reported that GPM6A showed a trend of dysregulation in schizophrenia [ 10 ].
Acteoside downregulated the levels of IL-6 ( Figure 2 A) and TNF-α ( Figure 2 B) in HMEC in a dose-dependent manner ( P < 0.01), which showed a trend similar to the release of adhesive molecules.
The monocyte compartment was further characterized: CD64 and CD11b expression levels resulted similar between the two groups, while HLA-DR showed a trend towards reduced expression in the unvaccinated cohort (Fig. 2C ).
Our results showed a trend towards increased central subfield macular thickness CSMT of 30% from baseline CSMT in the no injection group after the surgery.
Interestingly, while male animals only showed a trend toward an anorexigenic effect and lower respiratory exchange ratio (RER) upon CNO administration compared with control littermates ( Figure 6, E–G ), female mice significantly and acutely responded with a decrease in food intake (16.2% ± 0.1% reduction over dark phase and additional 30.7% ± 0.1% reduction during light phase) and concomitant RER shift toward increased lipid utilization following CNO application ( Figure 6, J–L ).
TGF-β–treated SSc fibroblasts demonstrated a significant reduction in TGF-β–induced α-SMA expression ( P = 0.03) and showed a trend toward reduced Col1a1 expression, whereas no reduction in fibrotic gene expression was observed in healthy control fibroblasts ( Supplemental Figure 4 ).