“showed a trend”

A post hoc analysis of KEYNOTE-240 showed a trend toward a greater efficacy benefit in the Asian subpopulation versus the overall cohort [ 53 ], consistent with the significant improvements in the OS, PFS, and ORR observed with pembrolizumab versus placebo in the KEYNOTE-394 study in Asian patients [ 29 ].

From their results, they found that fasting was well-tolerated, improved the patient QoL over the course of the cycles, and even showed a trend in reduced hospitalizations and improved hematological parameters [ 60 ].

ACTA2 as well as LMOD1 , previously connected to smooth muscle contraction, showed a trend to be upregulated after 24 h without stretch but only reached significance on rigid plates.

Levels of il1b showed a trend toward increased levels without reaching statistical significance ( Fig. 3F ).

Although our results showed a trend towards an effect, they did not reach a statistically significant difference and may require more cohorts to confirm in the future.

Many predicted metabolism functions showed a trend toward negative correlations ( R value of less than −0.5) with BA and AN, such as amino acid metabolism, carbohydrate metabolism, glycan biosynthesis and metabolism, lipid metabolism, the metabolism of cofactors and vitamins, and nucleotide metabolism (Table S3).

The levels of A20 showed a trend of downregulation with age in ovaries of 3- to 22-month-old rats ( Figure 5 A,D), although levels in 9-, 12-, and 22-month-old rats were slightly downregulated compared with those of 3- and 16-month-old rats.

The results show that the extraction rate of polysaccharides showed a trend of first increasing and then levelling off with the increase of cellulase addition, and the extraction rate of polysaccharides from MOL reached a maximum of (10.75 ± 0.14)% with an addition amount of 0.8%.

Longitudinal Analysis Longitudinal analysis of our cohort during the follow-up time showed a trend of thickening of the GCC in the LHON group in a central circle ( Figure 4 ).

A forest plot showed a trend of a non-linear dose-response association between Hct levels and ischemic vascular events in male patients.

Immunofluorescence staining with Ki67 showed a trend of higher proliferative activity of HSE in comparison to K4IM, but significantly confirmed the suppressive effect of NP.

They also had lower quality of life at the time of enrollment but showed a trend toward deterioration of the quality of life at the follow-up measure.

As the same time, the combination of platinum and PARP inhibitor veliparib also significantly improved PFS and showed a trend towards improved OS for patients with mTNBC [ 19 ].

The drug was well tolerated and showed a trend for clinical improvement associated with lower increases in CD19 + B cells and greater decreases in CXCL13 and MIP-1β from baseline to week four [ 87 ].

As an example, a subgroup analysis of the RECOVERY data for patients without the use of corticosteroids (indicative of earlier disease stage) showed a trend toward fewer deaths at 28 days in the CCP versus the control groups (19% vs. 24%, respectively).

found in their study that overall, ERAS did not show a significant difference in morbidity, but showed a trend towards reducing local complications [ 8 ].

Conclusions In conclusion, the results of this study showed a trend of reduction of macular vascular density in superficial plexus in eyes operated for RRD, with more impressive decreases for Macula-OFF, even following a successful anatomical repair.

0.6694; p = 0.2256) showed a trend toward being higher for the chronic compared with the acute subgroup, and while the diagnostic accuracy was significantly higher in the former subgroup (18.2397 vs. 4.2660; p = 0.0373).

Furthermore, the research showed a trend in the student’s preparedness for WIL placement, whereby they felt less prepared for their first and more prepared for their most recent WIL placement (Twinley, 2012 ).

LowSupp had the greatest Ct.BMD of the three groups and showed a trend for decreased resorption and formation in the cortical region, while OPSupp had the lowest Ct.BMD and showed a trend for increased formation in both the trabecular and cortical regions.

While subgroup analysis of 3,096 PAD patients (2,838 symptomatic PAD, mean age 66 years, 30% female, 36% diabetes) showed a trend toward a slightly reduced rate of cardiovascular events the combination of ASA and clopidogrel was associated with an increase in minor bleeding complications.

Examining the entire population, we found no significant associations with severe asthma, although those homozygous for minor A allele (AA genotype) showed a trend for significance in females (OR = 1.48 [95% CI = 0.86–2.52]), but not males (OR = 0.87 [95% CI = 0.46–1.63]; Supplementary Table 3 ).

Both blue and green food webs showed a trend of decreasing nestedness with increasing elevation (Fig. 5 ).

Serum growth-related parameters With an increase in taurine content, the GH levels in serum showed a trend of increase (0.4–1.2%) and subsequent decrease (1.2–1.6%, Figure 2A ).

Although position of employment did not reveal significant differences among the groups examined, both versions of the BTI showed a trend towards a difference in the overall Reaction subscale.