“showed a trend”

However, probiotic administration showed a trend towards improvement in some subscale indicators of bowel function, suggesting that further studies may be needed [ 9 , 18 ].

In addition, Cryo-EM acquisitions systematically showed multi-layered (or multi-lamellar) vesicles, representing 10–30% of total EVs, whose fraction showed a trend of decrease in the ectopic conditions compared to Mock (Fig. 2 D).

With the increase of temperature, the total phenolic content showed a trend of increasing and then decreasing.

At 12 °C, the content of hydrocarbons showed a trend of first decreasing and then increasing.

The control and treatment groups that were administered oseltamivir via gavage showed a trend toward weight gain during the intervention period.

plantarum HA119 showed a trend towards higher plasma HDL concentrations compared to the placebo, indicating the potential effect of these bacteria on serum lipids.

Finally, the fact that the DGOU classification showed a trend toward significance for its association with vertebral collapse should also be noted.

Additionally, in murine models, combination treatment with anti-LAG3 and anti-PD1 showed a trend toward improved survival compared to anti-LAG3 alone, and LAG3 knockout mice showed an improved response to treatment with anti-PD-1 compared to their wild-type counterparts [ 132 ].

However, the SCZ showed a trend of a higher number of extreme responders.

As a whole, the number of neurons in the ML showed a trend toward increased density from the anterior to posterior cerebellum, and was especially evident for the NeuN-positive displaced granule cells (Fig. 6 A-C, G-I).

The tumor volume in each group showed a trend similar to that of the first subcutaneous tumor model (Supplementary Figure. 4B and Supplementary Figure. 4C).

[ 36 ], but the unsaturated fatty acids showed a trend towards a higher content of polyunsaturated versus monounsaturated compared to those obtained in the aforementioned work.

Empagliflozin, when compared to placebo, showed a trend toward reduced atrial fibrillation risk with a risk ratio of 0.91 (95% CI: 0.75-1.10).

Subjects in all three groups showed a trend (non-statistically significant) for reduction in the IAEM scale for acne lesions, and there was also a trend towards a numerically higher reduction of inflammatory lesion count from baseline in Group C compared to A and B.

Again, it should be noted that a trend towards a decreased risk was shown in seven out of the nine studies, while the New Hampshire and Molecular epidemiology of BC studies showed a trend towards an increased BC risk.

The total SCFAs content showed a trend of FOS group > FVRPV group > CK group, which corresponds to the change in pH value of the fermentation broth.

Although Other patients also showed a trend toward a decreased level, it did not reach statistical significance, likely because the volumes were already beginning to decrease before shutdown.

These results showed a trend towards better OS trend than the Checkmate 141 study 13 and Japanese clinical use reports, 21 , 22 but comparable PFS.

Participants with a previous history of cardiovascular conditions showed a trend of larger increases in HSI S2 from pre-termination to post-termination events, compared to those with no known history ( Figure 7A and B ).

Furthermore, in the supernatant of DHT-induced RWPE-1 cells, the content of secreted IL1B, IL6, TNF, and IFNG showed a trend similar to that of the mRNA transcript levels ( Figure 4E ).

However, the TCRβ diversity analysis showed that the mean level of TCRβ diversity was not significantly different between patients with relapsed and non-relapsed patients, and although patients with high TCRβ diversity (cut-off: 5.26) showed a trend for better iDFS, the difference was not statistically significant ( S5 Fig. ).

And in KEYNOTE-062 trial, pembrolizumab demonstrated clinically meaningful efficacy in patients with a CPS of 10 or higher for PD-L1, with better survival in patients with high PD-L1 expression, indicating that patients with higher levels of PD-L1 expression showed a trend toward better survival ( 42 , 43 ).

Conversely, Smc2 depletion showed a trend towards DIF increase in one of the days (Day A, auxin added 2 hours before nucleofection (Fig. 3)), where it reached +33 % (Ace2 deletions), +75 % (Ace2 inversions), +61 % (Ctcf deletions), +63 % (Ctcf inversion).

Lobectomy showed a trend toward higher LCSS compared with sublobar resection, but the difference was not significant (SHR, 0.696; 95% CI: 0.466–1.040, p = 0.078) (Figure 4b ). 4 Discussion Since the 1970s, radiotherapy and chemotherapy have replaced surgery as the standard treatments for limited‐stage SCLC (L‐SCLC).

65 Similarly, a 48-week trial of lovastatin in 77 PD patients, showed a trend in reduction of UPDRS part III scores which did not reach statistical significance. 66 Inflammatory biomarkers were not assessed as a part of either of these trials.