A small and slightly significant difference ( p = 0.0243) was observed upon mutation of both the G-box and GATA elements, however a triple mutant (G-box, GATA, and CAAT) was not significantly different than ELIP1 WT.
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In contrast to LoF variants, this represents only a slightly significant enrichment ( P = 0.025), emphasizing that while missense variants are likely to be the cause of ID in some cases, their interpretation is much more challenging than that of LoF variants, as has previously been shown [Grimm et al., 2015 ], even following stringent preselection for likely damaging variants.
Spatial analysis When all Atlantic and Mediterranean colonies were analysed, the slope of the regression between distance matrices was estimated to 0.027, with a slightly significant association between matrices (P = 0.025) and suggesting a low isolation by distance pattern.
A slightly significant association with TNBC was also observed in carriers of the heterozygous G/C genotype (OR = 1.51, P = 0.025).
Statistically, the difference between VtoV values in the period 1979–2009 and those in 2010–2014 is slightly significant ( p = 0.025); values in 2010–2014 do not result to be different from those in the time span 2015–2021 ( p > 0.05).
Posttreatment levels of groups A and B are not significantly different from each other (p = 0.581), whereas the difference between the posttreatment levels of group B and the non-malignant controls (group C) is slightly significant (p = 0.025).
The correlation was not statistically significant for the first three waves ( P = 0·285, 0·538, and 0·532, respectively) and slightly significant for the fourth ( P = 0·026, adjusted r 2 = 0·096).
We also analyzed the breast cancer-specific survival (BCSS) and slightly significant differences were observed (χ 2 = 7.285, P = 0.026, Figure 1B ).
As expected, this ratio is significantly lower ( p-value < < 0.001; Fisher’s exact test) in the deep portion of the tree and the comparison among domestic branches reveals slightly significant differences ( χ 2 p-value = 0.026) (Table 3 ); in particular the ɷ ratio of A is much higher than previously reported (ɷ = 0.049) [ 17 ].
3.1.1 Differences and interrelationships in participation preferences between decision‐making levels The variation in the distribution of participation preferences between decision‐making levels is slightly significant ( χ 2 = 7.30, p = .026).
However, the interaction between low IDO and low IL4I1 expression achieved a slightly significant decrease in hazard (hazard ratio = 0.3301, p = 0.0263). 3.
As shown in Figure 9 , the secretion of IL-1β cytokine from normal REF with first and second concentrations (groups) of microbial-extracted pigment was slightly significant compared with the control group: 2,067.5 μg/ml ( p < 0.0267) and 1,033.75 μg/ml ( p < 0.0348).
zosterophorum , the observed raggedness value of 0.163 was slightly significantly smoother (p-value = 0.027) than mismatch distributions simulated from the expansion population size model.
The litter size at day 5 was slightly significant higher in Duroc ( P = 0.027), and at day 21, the litter size of Pietrain progeny litters (14.5) was significant less than litter size in Duroc progeny litters (14.9, P = 0.015).
Furthermore, and except for PC3 in which a slightly significant decrease in methylation levels was detected after treatment with DAC alone or combined with TSA (Dunnet’s test, p = 0.027 and p = 0.012, respectively), no significant effects were found in methylation levels compared to mock cells in PCa cell lines, in line with bisulfite sequencing analysis results.
The same factors explained BMD when ANOVA was performed separately in each group (non-OP and OP patients), except for the additionally slightly significant P1NP in OP patients ( p < 0.027, α = 0.61).
For sepsis-related admissions, the rate of Gram positives (+) showed a slightly significant downward trend (from 9.94% to 9.22%; p = 0.027, Figure 6 A1, full description in Table S5 ), while the rate of Gram-negatives (−) showed a significant upward trend (from 14.37% to 17.2%; p < 0.001; Figure 6 B1, full description in Table S5 ).
In the control group, a slightly significant decrease (mean difference=9.679, standard error=3.754, P<0.027, η2=0.140) was also found in T3 compared with T1.
detected a slightly significant negative correlation between BMI and serum iron levels (r=-0.234, p=0.027) among obese women of reproductive age. 23 In contrast to their findings, despite the high rates observed in our study, statistical analyses showed that the difference was not statistically significant (χ 2 =0.571, df=2, p=0.773).
However, there was a slightly significant negative association between subjective sleep quality and EPDS scores in two models ( b = −2.20, p = 0.028 and b = −1.97, p = 0.049).
Accordingly, statistical analysis showed a slightly significant negative correlation between ERG amplitudes and age for LA b-wave (rho = -0.59; p = 0.028) and flicker (rho = -0.54; p = 0.046) amplitudes.
In the Pre-Rif, there was a slightly significant tendency for farmers growing modern varieties to sell a bigger part of their production (21.5% vs. 13.5%, F = 4.92, df = 1, P = 0.028).
Results for each dataset can be found in Additional file 5 . Predictive performance and feature stability Comparing the mean AUC-ROC to the number of statistically similar models showed a slightly significant and decreasing association ( p = 0.029; Fig. 5 a), that is, the better the best model performed, the less statistically similar models were observed.
For AZM, the results did not confirm the significant reduction observed during the first experiment in plasma, but another non-reproducible slightly significant reduction of viral RNA yields in lungs was detected ( p = 0.0290).
Elevated VRC and CSF MICs were obtained for all the isolates although slightly significant lower VRC MIC GMs were observed for R. microsporus than for the other Mucorales (4.59 mg/L vs. 8.00 mg/L, respectively; P = 0.0295).