While a stepwise pattern was observed in FST, such that STZ-UCMS mice showed the highest immobility times, the effect of UCMS on immobility was only trending toward significance.
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3 C ), although these effects were not statistically significant or trending toward significance.
The ERGM analysis highlights the role of animal movement as a primary risk factor for transmission (although the coefficient for animal movement in Cluster C was only trending toward significance).
Salsalate treatment induced a significant increase in phosphorylation of acetyl-coenzyme A (CoA) carboxylase (ACC) at Ser79, but this was accompanied by an increase in total ACC levels (trending toward significance) ( Figures 5 C and 5D), resulting in an unchanged pACC/ACC ratio ( Figure 5 D).
The implementation strategy bundle was also associated with a substantial improvement in PrEP fidelity but was only trending toward significance.
We found three features that were statistically significant or trending toward significance in the preliminary study: basal lamina “projections without contents,” number of microvilli, and presence of budding endothelial vesicles.
In 22q11Dup, the association between lifetime acute and chronic stressors with the presence of general symptoms was both trending toward significance.
Two‐sided p ‐values of < .05 and two‐sided p ‐values of < .15 were considered significant and trending toward significance, respectively.
For this reason, relationships with a p-value between 0.05 and 0.10 were additionally considered as trending toward significance [ 36 ].
In a per-signature analysis, UPFL tumors were significantly enriched, as compared with UPPL tumors, for numerous subsets of T cells, including CD8 + , central memory, and effector memory, while trending toward significance for T follicular helper cells and γδ T cells (Bindea) ( Figure 4, C–G ), the latter of which are important for adaptive immunity at mucosal surfaces ( Figure 4G ).
Scores for depression (CES-D), PTSD (PCL-5), and trait anxiety (STAI) were slightly higher, trending toward significance for MCUs.
Our study found that age and BMI are statistically significant with BI‐RADS and are trending toward significance in saliva Cd and smoking.
However, despite the small sample size, we were able to demonstrate statistically significant outcomes in patients who were initiated on both GLP1 RA and SGLT2i’s, and we were trending toward significance with the GLP1s plus Metformin sample as well as with the total population.
All three variants that were trending toward significance in the susceptibility GWAS are of low frequency (Table 1 ) and will require larger sample sizes for validation.
Five additional metrics were noted to be trending toward significance.
Statistical significance for GLM analyses was noted as P -values of less than 0.05, and P -values between 0.05 and 0.06 were noted as trending toward significance.
All meta-analysis results were insignificant, but with narrow CIs and results trending toward significance.
Performance on the subcategorization task, although not significantly associated with damage to the Broca's area ROI, was trending toward significance, although this was only the case when lesion volume was not added as a covariate (see Matchin et al., 2023 , for detailed discussion of the importance of lesion volume to the mislocalization of syntactic comprehension deficits in aphasia).
In iron-replete conditions, there was no significant difference between the lpdA mutant expressing empty vector and WT eV, and Δ lpdA +lpdA , though the results were trending toward significance ( Fig.
In addition, results of the first interim analysis showed significantly fewer AEs occurred in the TAMP arm, with a 6-month survival difference trending toward significance. 28 Conclusion In this combined analysis of the RR1 (dose escalation) and RR2 (observational) studies, TAMP-delivered gemcitabine was found to be potentially safe, feasible, and provided potential clinical benefits in patients with LAPC.
Patients experiencing homelessness also had significantly lower discharge mOMT scores (0.42, 95% CI: 0.38-0.46 vs 0.48, 95% CI: 0.46-0.51; P = 0.01), with values trending toward significance in both patients with new and pre-existing diagnoses.
For the cerebellum for both the raw volume and when controlling for ICV, post hoc analyses suggested that slope differences were trending toward significance for HC relative to FAE ( P ’s < 0.09).
Third, although only significant in the univariable analysis (but trending toward significance on multivariable testing), speaking Spanish was associated with higher receipt of testing, a finding that has not been commonly reported in the literature.
In the current study, it appears that this was trending toward significance for Cntnap2 KO females.
Mechanistic associations between cardiac structure and function and measures of physical fitness Within the total cohort, a statistically significant, moderate, positive association between the Q̇ and relative V̇O 2 ( r = 0.61, p = 0.04; Figure 2 ) at the GET, was found, with associations trending toward significance between resting LV mass index and V E at the GET, and handgrip strength (Table 7 ).