Barely Significant
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“very close to significance”

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In the literature

Pearson index All patients ( n = 71) (Table 3 ) Integrated kisspeptin plasma concentrations were positively correlated with kisspeptin pulse frequency and negatively with cortisol plasma concentrations while were very close to significance with integrated LH plasma concentrations; integrated LH plasma concentrations were significantly correlated with BMI, E2 and insulin plasma concentrations and were negatively correlated with cortisol plasma concentrations; LH pulse frequency was positively correlated with E2 plasma concentrations and kisspeptin pulse frequency and negatively correlated with cortisol plasma concentrations; glucose plasma concentrations were positively correlated with insulin, cholesterol and cortisol plasma concentrations.
This outcome was not observed in OS; however, significance was maintained when adjusting the result with the variables age and sex ( p -value: 0.044, HRa: 2.832, IC HRa: (1.029–7.794)), and it also remained very close to significance if the adjustment was performed by staging ( p -value 0.064, HRa: 2.597, IC HRa: (0.946–7.126)), as is shown in Figure 6 .
Hence, in the obtained final model, the season-treatment-physiological stage interaction is very close to significance, whereas the apiary-treatment-physiological stage interaction is clearly significant, as are the physiological stage-apiary and the treatment-apiary interactions, and the apiary factor.