Risk factors for coronary artery disease progression: A retrospective cohort study of clinical and biochemical predictors.

Medicine (Baltimore) · 2025 · PMC12151003 · PMID 40489866

Europe PMC DOI

hedged sentences

0.0930

closest p · 1.9× alpha

0.0940

boldest claim

The sentences

approaching significanceP = .093so close (0.05 < p ≤ 0.1)

Elevated interleukin-6 levels (OR = 3.051, 95% confidence interval: 1.164–7.999, P = .023) and triglycerides (approaching significance, odds ratio = 1.126, 95% confidence interval: 0.980–1.293, P = .093) were identified as key predictors of CAD progression.

also in 1,619 other papers

approached significanceP = .093so close (0.05 < p ≤ 0.1)

TAG also approached significance as an independent predictor (adjusted OR = 1.126, 95% CI: 0.980–1.293, P = .093).

also in 5,298 other papers

showed a trendP = .094so close (0.05 < p ≤ 0.1)

did not reach statistical significanceP = .404not close (p > 0.1)

Troponin levels showed a trend towards elevation in the progression group (mean 0.023 μg/L, SD 0.009 vs 0.021 μg/L, SD 0.009; P = .094), while BNP and NT-proBNP were also elevated but did not reach statistical significance ( P = .404 and P = .054, respectively) (Table 2 ). 3.3.

also in 33,481 other papers

marginally significantno p-value reported

By expanding the sample size and incorporating additional biomarkers into multivariate models, we found that elevated IL-6 levels and TAG (marginally significant) were important risk factors for CAD progression.

also in 15,096 other papers

near-significantno p-value reported

Elevated interleukin-6 and triglycerides levels are significant or near-significant predictors of CAD progression.

also in 1,659 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.