Excerpts

NOAC showed a nonsignificant trend for a lower risk of ICH when compared to warfarin (HR: 0.843, 95% CI: 0.523–1.321, Figure 3 , panel A).

However, we can find a decreasing trend of almost all oral OA medications from 2004 to 2008 except for opioid.

All studies showed a trend towards a lower peritoneal recurrence rate after prophylactic HIPEC.

Although the significance remained unchanged only after removing either of Guerrero et al.’s [ 29 ] or Toker and Kömürcü’s [ 18 ] study, the sensitivity test still showed a trend for anxiety reduction in the music group ( Figure S1 ).

However, meta-regression revealed a nonsignificant trend for increase in the anxiety-reducing effects of music interventions with increasing maternal age.

A marginally significant interaction was observed between baseline PEF SR percentiles groups and obstructive respiratory diseases (diagnosis of COPD and/or asthma) in influencing the risk of developing frailty at follow-up ( p interaction = 0.05).

Furthermore, ESBL-producing Klebsiella and Enterobacter species appeared with an increasing trend in recent years.

Complete device endothelization has been observed after 90 days in animal models, but this time may be protracted in humans, and interindividual variability may be significant, adding uncertainty regarding the optimal type and duration of the antithrombotic therapy after LAAO.

On the contrary, a more recent patient-level meta-analysis including the recent results of the ENTRUST trial, showed a trend (although not significant) towards higher risk for stent thrombosis with dual therapy.

For internalizing problems, somatic unexplained symptoms decreased over time where depression and anxiety showed an increasing trend, stronger in some subgroups than in others.

Overall, stress exposure showed a decreasing trend over time across subgroups but for those groups with a curvilinear trend they peaked during mid-adolescence.

The mortality rate from 2004–2015 was 0.064 individuals per 1,000,000 with an increasing trend of 0.002 per year.

All quoted p -values are two-sided, with p ≤ 0.05 (*), p ≤ 0.001 (**), p ≤ 0.0001 (***), and p ≤ 0.00001 (****) being considered statistically significant for the first and highly significant for the others. 3.

Resistance to metronidazole has increased worldwide; however, in Korea, a decreasing trend in metronidazole resistance was observed in several studies [ 10 ].

eBAC approached significance in this model.

Finally, only PCS score significantly predicted composite scores based on ‘Gastric and cardiovascular’ symptoms, though eBAC was only marginally non-significant.

In addition, regression analysis indicated that only the duration of a single training session ( p = 0.025) significantly predicted the effects of the intervention on oxygen consumption, while time on dialysis ( p = 0.078) and total training volume ( p = 0.084) showed a trend ( Table 3 ).

The effect was greater in ECs from MM patients than in those from MGUS patients, although the difference was hardly significant ( Figure 4 E).

The potential implications of this concept may be significant.

However, it shows a slightly significant difference among the groups.

To prevent the exclusion of predictors with borderline significance, a p -value of 0.100 rather than 0.050 was used for the inclusion of variables in the multivariate model.

In DMD patients, a positive trend in improvement of muscle function, as well as other measured physical functions was observed after 48 weeks of ataluren treatment.

Patients that initially presented with DIE showed a trend to also subsequently present with DIE (29/54: 53.7%) at the next surgery.

Statistical significance was set at p < 0.05, while the p value of <0.1 was considered a statistical trend. 2.2.

Fenofibrate did not reduce, but induced an increasing trend in the intracellular lipid content of macrophages.