Barely Significant

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Therefore, in this study, the PNP solution was adjusted to different pH values, including 2.43, 3.23, 4.08, 5.15, 6.14, 7.02, and 8.09, to investigate the effect of pH on the adsorption of p-nitrophenol by the GO-ATT composite, and the results are shown in Figure 10 B, which shows that the adsorption of PNP by GO-ATT composite showed an initial increase and then a decreasing trend.
Additionally, the Gibbs free reaction energies (Δ G RXN , kcal/mol) for the [2 + 2] cycloaddition between N=C=N and Ge=G15-Rea exhibit an increasing trend: Ge=N-Prod (−41.4) < Ge=P-Prod (−23.2) < Ge=As-Prod (−17.7) < Ge=Sb-Prod (−14.9) < Ge=Bi-Prod (−11.0).
Upon treatment with 25 mg/kg of compound 12 , there was an increasing trend in the infiltration of total immune cells (CD45 + cells) ( Figure 4 C), and the tumor infiltration of total TAMs, TAMs with the M2-liketumor-promoting phenotype (CD206 + TAMs), and immunosuppression TAMs (ARG1 + TAMs) in CD45 + cells was significantly reduced ( Figure 4 D–F), accompanied by the marginal upregulation of TAMs with the M1-like phenotype (CD86 + TAMs, MHC II + TAMs) ( Figure S3A,B ).