Barely Significant

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Over the last few decades, there has been an increasing trend in the incidence of AD and food allergy, especially noticeable in highly developed countries, which is associated with a strict hygiene regime, increased use of detergents, low number of children per family, altered nutritional habits, frequent antibiotic therapy, low incidence of infectious diseases, and high numbers of Cesarean sections [ 9 ].
Gamma-linoleic acid, in which the causal estimates were significant in the allele score-based MR, showed marginally significant causal estimates with notably high odds ratios in the summary-level MR, whereas adrenic acid, which showed null findings in the allele score-based MR, showed significant causal estimates for higher risks of both CAD and MI in the CARDIoGRAMplusC4D data. 4.