Excerpts

In conjuction herewith the expression of α-SMA and KIM-1 as markers of pre-fibrosis and tubular damage were also reduced, albeit of borderline significance.

However, we found a weak trend of the core area of home range size to increase with decreasing biomass of preferred plants, suggesting that females adjust the size of the core area of their home range to the amount of resources they can obtain.

This result can also be regarded not only as statistically but also as practically significant, as there is a 0.08 difference in EQ-5D index scores between the lowest degree of the Morisky score indicating poor medication adherence, and the highest score indicating best medication adherence.

We find that TQ+DG show highly significant potential to reduce tumor size and weight in tumor-bearing animals, much higher than either treatment alone or no treatment.

Finally, the main effects of electrode site were significant or marginally significant in all these time windows; there were no two-way interactions between electrode site and the other two factors; there was no three-way interaction among all factors.

The effect of seed rain intensity on species richness was significant from the 1 st to the 3 rd time periods, marginally significant in the 4 th time period and non-significant in subsequent time periods ( Table 2B ; Figs. 1B and S1B ).

Nevertheless, an ANCOVA model adjusted for sex, age at RA diagnosis, follow-up time from disease diagnosis, and classic CV risk factors, disclosed a marginally significant p value (0.052) when we compared the IFN-γ levels of patients carrying A allele with CV disease against patients who did not develop CV disease at the time of the study ( Table 8 ).

With our sample the empirical results suggest that regions which are estimated to explain a little over 1% of the variance can be detected at the suggestive level, whereas regions estimated to explain around 2% of the trait variance may be significant at the genome wide level.

In fact, a recently published study using selenium and vitamin E in a rat model of prostate tumorigenesis showed a similar finding, that vitamin E treatment showed a marginally significant increase in prostate tumor formation [65] .

Table 4 lists several highly significant pooled effects, although moderate to important levels of statistical heterogeneity were typically present.

Distinguishing between these or other molecular mechanisms is a highly significant but challenging problem which solution will enable to predict clinical risk of new or investigational drugs.

The correlation was highly significant for most respiratory function parameters with respect to five of the seven sensors composing the array.

Thus, the expression of IFN-γ, IL-2 and TNF-α was significantly greater in the multifunctional (double & triple) populations that in any of the mono-functional populations and there was an overall trend of higher quality of response as the cells increased in function.

The relationship of the species richness of all species to carbon stocks showed no or only marginally significant patterns, both when all plots and only the agroforest plots were considered ( Figure 2 , Figures S1 , S2 , S3 ).

There was a significant hand×tray interaction along with a significant interaction between group and tray and a marginally significant group×hand×tray interaction.

Pre-miR-223 induced a highly significant 64% increase in cell migration.

Our data indicate a decreasing trend in testes size of L. cinereus found dead at wind turbines from July through October.

The prevalence of suspected hepatitis B was highest among participants aged 20–49 years and showed a trend to a sharp decrease from 20 years to zero years old.

This is a highly significant reduction, as the rate was approximately 9%–12% for a similar age group prior to 1992 [8] and equals a reduction of an estimated 1,577,391 HBsAg carriers and a savings of US$17.8 billion for treatment of HBV infections in Zhejiang Province.

DTI Results When corrected for multiple comparisons at p<.05, permutation analysis revealed highly significant reductions in FA in NF1 patients relative to controls, which were spread broadly across the entire brain ( Figure 3 ).

As expected, its expression, even if with slightly different levels, showed a trend similar to P33 in both WT and AfP33 strains ( Fig. 1D ).

IL-2 showed a highly significant increase in MFI in the IFN-γ + TNF-α + and triple producers (ρ<0.001).

Both biochemically and clinically, a single heterozygous change in URAT1 may be significant.

A stretch of negative log 2 ratio values is typically representative of copy number deletion, while a positive trend denotes a copy number amplification.

Haplotype analysis revealed that a haplotype of CRHR1had a highly significant positive association with recurrent MDD, a haplotype with alleles G-G-T respectively the SNPs of rs1876828, rs242939, rs242941, was significantly over represented in the recurrent MDD group than in the control group (chi-2 = 10.059, df = 1, P = 0.016), which suggested that carrying this haplotype might increase the probability of developing recurrent MDD in Han Chinese population.