Excerpts

Results Indicators for effective field application of malaria prevention measures As illustrated on Fig 1 , there was a strong increase of prevention measures against malaria from 2010 to 2013 in Abobo with highly significant results.

However, the coefficient correlation is barely significant, and other environmental factors, such as the North Equatorial Current, the Kuroshio [ 18 ], and biological conditions, could also play significant roles.

These data were confirmed at the protein level by ELISA, which showed a highly significant increase of CXCL10 in all the NHOKs ( Fig 4 ).

Furthermore, betaine was additionally associated in Health2006/08 and barely missed statistical significance in Inter 99 (FDR = 0.06).

The difference in mortality rates was highly significant (n = 400 P-Kisumu <0.0001, χ = 573, df = 1).

The incidence rate showed a slightly increasing trend from 2001 to 2004 and then increased sharply each year from 2005 to 2012; however, the change in the trend was not significant according to the joinpoint regression analysis.

However, there was a marginally significant main effect of severity, in that participants in the negative condition gave higher ratings (M negative = 2.49, SD = 1.71) than participants in the neutral condition, (M neutral = 2.04, SD = 1.72), F (1,196) = 3.47, p = .06.

There were highly significant differences among study sites as well as between urban and peri-urban sites for both, rodent and parasite communities.

Twelve regression analyses were conducted but none of the conducted tests approached significance ( F s<1.8, p s>.2).

Given the highly significant association between MSI and methylation of the MLH1 promoter in sporadic endometrioid endometrial cancers [ 32 ], the strong correlation observed between methylation score and MSI was expected.

In Denmark antidepressant use increased while the use of antipsychotics, anxiolytics and hypnotics decreased in 2000–2012 among persons with dementia.[ 7 ] In our previous study including all community-dwellers who received a clinically verified AD diagnosis in Finland during 2005–2011, we detected an increasing trend of antipsychotic use, no changes in antidepressant use and decline in BZDR use.[ 4 ] Our study on the regional differences of the same cohort showed regional variation in antidementia medication use across university hospital districts,[ 8 ] but it is not known if similar regional variation exists in psychotropic use.

This hypothesis was confirmed, as all fixation duration measures except TVT were significantly increased after an incongruent preview as compared to a congruent preview (with marginal significance for TVT; Tables 4 and 5 ).

On the contrary this difference was apparent in men.

The effect of the application of the whitening strips for these shorter time periods on bovine dentin flexural strength and fatigue resistance was still highly significant.

Adjusted analysis showed a trend for increasing childhood vaccination with time.

This variable was marginally significant in the rural sample (aOR: 0.55, 95% CI 0.27, 1.17).

Soil particle-size distribution and fractal dimension In this study, land-use pattern was found to produce highly significant effects on the fractal dimensions of PSD, indicating that it is a primary factor influencing the PSD of alluvial fans in collapsing gullies.

Serum markers discriminate histological fibrosis stages All markers showed highly significant correlations with histological fibrosis stages ( S1 – S3 Figs).

When GWAS was performed a second time to include marker scores for rym4 and rym5 , only rym4 resulted in a highly significant association in both years (-log10( p ) values of 4.4 and 4.9 for 2009 and 2010 respectively).

While the average difference is modest, the p-value is highly significant because of large sample sizes.

HTN was associated with a decreased risk with borderline significance for peritonitis only on multivariate analysis of all HD patients.

Analysis of the rate of wound healing between Gα 11 KO/Gα q -WT control and Gα 11 KO/Gα q -eKO animals demonstrated a significant shift at all time points, leading to a highly significant difference in the wound healing curves ( Fig 4D ).

An increasing trend in precipitation, which is found for both models, can lessen or counteract a trend toward increasing dryness in SPEI.

A positive trend in precipitation can also dampen the increase in E 0 through the complementary relationship [ 89 , 90 ] by increasing available moisture, thereby impacting EDDI.

Finally, corresponding differences in gray and white matter morphometry between early blind and sighted controls can also be easily visualized confirming an overall trend for decreases in morphometry measures rather than increases (inner rings).