Barely Significant

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Discussion The main findings of our study are: (1) There was a modest but significant decrease in PI and RI in the left MCA after haze exposure, along with notable decreases in PI and RI after haze exposure in the right MCA showing a trend towards significance but, perhaps because of a small sample size, did not achieve statistical significance; (2) On subgroup analyses, the differences in mean PI and RI values after haze exposure were pronounced in the symptomatic group; (3) Participants who reported new psychosomatic symptoms during haze exposure developed a significant decrease in PI and RI on TCD while the asymptomatic volunteers did not show any significant change in these TCD parameters.
The 2–4 years old already showed a decreasing trend in PCV10 (VT)-IPD during the pre-period, which along with slowly increasing PCV10 coverage among the <5 years old during the post-period explain the lower vaccine effectiveness among the <5 years old, compared to other observations.