Excerpts

P for trend tests examine whether there is a significant trend across ordered categories like grade levels and socio-economic status.

Accordingly, reports from the Iran National Cancer Registry suggest an increasing trend in 2009–2014 [ 63 ].

While this metric enables quantitative performance evaluation of topic modeling, it has the limitation of showing a decreasing trend as T increases, theoretically reaching its lowest value when the number of topics equals the number of documents [ 28 ].

At the temporal level, the ecological space configuration optimization levels of the four cities showed a trend of fluctuating growth year by year, as shown in Table 3 .

Overall, the gap in ecological space quality among cities in the region is gradually narrowing, reflecting a positive trend of collaborative development. 3.3.

From an infection control perspective, these findings suggest a positive trend, and further studies are needed to determine the ICU characteristics contributing to these outcomes.

Hence, these findings should be interpreted with caution due to the lack of data from the first 5 years; however, in terms of infection control, these results suggest a negative trend.

The impact of digital existence and lifestyle on individuals’ social psychology and behavior has long transcended the realm of information, thus making the entry point of digital inclusion more practically significant and academically promising.

The main findings are as follows: First, negative life experiences negatively affect sense of security, and this adverse impact shows a decreasing trend from 2013–2017, whereas an increasing trend from 2017–2021.

Thus, it confirms that digital inclusion negatively impacts on sense of security, and this negative impact shows a decreasing trend over time. 4.2.3 Moderating role of educational level.

In the univariate analysis for competence, controlled regulation showed a trend toward significance with an OR of 1.16, while autonomous regulation also indicated a similar trend with an OR of 1.22 (see S5 Table ).

The age-standardized TB-related mortality in Eastern African countries has shown a decreasing trend over time.

Wajir, Meru, Mandera, and Bomet observed an increasing trend in TB-related death incidence from 1990 to 2021 “ S3 Table ”.

This indicates that AEs are not limited to the early stage of medication use but are widely distributed across a longer time frame, with a decreasing trend in the frequency of occurrence over time.

Importantly, socio-economic differences in LC mortality are predicted to persist in future years, whereas marginally significant regional differences would remain relevant for BC mortality.

Observed and estimated age-specific rates aged between 45 and 75+ from 1981 to 2019 indicate an increasing trend in NS prevalence, with a more homogeneous and faster increase among men over the considered period (S2 Fig in S1 Text ).

The conclusion stating that "TRIBAL suppression in HepaRG resulted in ~5 times fewer nominally significant hits than in hepatocytes, suggesting either the possible loss of TRIBAL targets in HepaRG or lower quality data" could be strengthened.

Recent innovations in quantum communication protocol architectures have shown a significant trend of multidirectional expansion.

Despite statistical insignificance, a decreasing trend was observed from Upper-part (0.007 ± 0.005 mg/L) to Mid-part and Lower-part (both 0.006 ± 0.004 mg/L) ( Fig 2 ).

Notably, a highly significant correlation was observed between the retained three modules and Activated CD4 T cell, as shown in Fig 4 . 3.3 Significantly DEGs The results of differential expression analysis are presented in the form of volcano plot in Fig 5A .

Because HIV co-infection prevalence is highly significant among patients with TPE, do authors have any data about HIV infection or immune testing (CD4 cell counts...etc) in these cohorts?

Response: We defined P <0.05 as significant (not P =0.05), but acknowledge your concerns about P =0.05 being borderline significant, which can occur with a small mean ±SD difference due to the large sample size, and low variability in LIMA length as mean (SD) decreases with increasing sample size and low variability in data, making even minor differences more detectable.

(2018), "There is no definition of a trend toward statistical significance and, therefore, describing 'almost significant' results as a trend introduces substantial subjectivity" and constitutes biased reporting practices.

The characterization of p=0.05 as representing a "trend toward significance" requires correction.

Although the damage to porosity also shows an increasing trend, the overall variation is relatively small, mainly because the pore volume of the core is much smaller than its apparent volume.