Excerpts

The opportunity to intervene at the time of DOX chemotherapy to save a patient from acute or delayed cardiac dysfunction is extremely significant and could help in improved quality of life.

This study demonstrates that age has a highly significant independent effect on both LDI FLARE and CCM measures, urging the need to establish age-stratified thresholds when these techniques are deployed for the diagnosis of DPN [ 40 ].

Highly significant differences were found in our sample, with a 1.36 difference on average (on a ten-point scale) between the organization with the highest ratings and the organization with the lowest ratings.

In addition, there was a clear trend toward an increased incidence of deep or infratentorial CMBs with increasing number of MetS components; compared to patients without any MetS components, those having three or more components were almost 14.1 times more likely to develop new deep or infratentorial CMBs.

The lack of NKLAM protein was associated with less lung inflammation and the survival study showed a trend toward decreased mortality.

Firstly, a highly significant association of goal difference at full time with the goal difference at half time, with the expected positive sign, is found.

Our estimates further showed that institutional delivery is a highly significant determinant which increases the probability of birth registration.

In contrast, sperm viability did not show a clear trend during ageing; a significant decrease in sperm viability was recorded from 44 weeks to 56 weeks, whereas no significant differences were detected between 32 and 44 weeks, and between 32 and 56 weeks ( Fig 1C ).

The TMR ratios presented in Fig 4 , suggest there may be significant differences between dry and wet year TMR.

In addition to the extreme rate of loss, this study documents the targeting of elephants for their skin instead of the more common ivory, an increasing trend in Myanmar.

Our previous study showed that the SSR marker analysis revealed highly significant differences in genetic differentiation among accessions within Melilotus species accessions [ 21 ].

As hypothesized, interpretation bias as assessed with the recognition task became more positive by CBM-I training compared to CBM-I placebo, although this effect just fell short of significance after Bonferroni-Holm correction.

In adults, marginally significant effects on social anxiety were observed four weeks after CBM-I training [ 21 ] and significant effects at seven weeks follow-up [ 22 ].

Its results demonstrated a highly significant association of all three investigated SNPs with an overall susceptibility for UC.

RNA levels of the ligand placenta growth factor ( Plgf ) were upregulated ( Fig 1D ), whereas vascular endothelial growth factor ( Vegf )- a and - b only showed a trend of increase ( Fig 1E and 1F ).

Similarly, we observed an increasing trend.

Highly significant negative values of Fs and small positive values of R2 indicate population growth whereas positive Fs values can result from balancing selection, population bottlenecks or the presence of population structure [ 63 , 64 ].

The period effect does not show a clear trend, there are fluctuations in time, but it is not possible to identify a dramatic effect of any event in a year that determine a significant increase or decrease in relative risk of maternal death in function of the period.

The incidence rate of NEC in Sweden during 1987 through 2009 was 0.34 in 1,000 live births, with an increasing trend, partly explained by increased survival of the most premature but also seen in higher gestational ages (GA)[ 1 ].

In the same line, an intervention over 25 patients (mean age of 86 years) found, that a dietary supplement based on an oily emulsion of DHA-phospholipids containing tryptophan and melatonin showed a significant treatment effect for the MMSE, a positive trend for the semantic verbal fluency, and the olfactory sensitivity assessment, and as regards the nutrition evaluation, the supplemented group showed an improvement in the MNA in comparison with the control group [ 20 ].

However, if we excluded the loops connecting membrane-spanning α-helices, it was possible to observe a potential 3-TMS structural repeat with borderline significance, RMSD = 3.57 Å over a 60 residue alignment where TMSs 3–5 align with TMSs 6–8 (See Methods and S1 Fig ).

Of note, the prevalence of syphilis showed an increasing trend.

We found a highly significant difference in sensitivity of JRFL and REJO viruses to lectins, with REJO displaying relatively less sensitivity than JRFL.

This pattern of distribution was confirmed by Fisher exact tests of independence, which revealed that the relationship between sex and “brain type” was highly significant ( p = 7.4·10 −14 ), the relationship between major and “brain type” was highly significant ( p < 2·10 −16 ) and the relationship between combined sex-major and “brain type” was highly significant ( p < 2·10 −16 ).

Species-specific differences in food incorporation Our experiments did show a highly significant ‘species effect’, with incorporation and respiration rates of the isotopically-enriched food sources being more than an order of magnitude higher for the sponge as compared to the coral.