Barely Significant

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Comparing the percentage reduction of non-diabetic versus STZ-diabetic HDAd-LDLR treated mice revealed a significant impairment of the regression of CD68+ cells in STZ-diabetic mice; in non-diabetic mice CD68+ cells decreased by 77% versus a 57% decrease in STZ-diabetic mice (p<0.01) The percentage difference in plaque size regression between non-diabetic and STZ-diabetic mice also showed a trend to decrease less in the latter (36% vs. 51%, respectively).
As shown in Table 2 , the age-adjusted hospitalization rate (standardized to the WHO World Standard Population) of patients diagnosed with AKI exhibit an increasing trend, rising from 7.7 to 17.0 per 100,000 inhabitants between 2010 and 2019, while those of patients diagnosed with CKD display a decreasing trend, declining from 54.1 to 37.1 per 100,000 inhabitants.
In terms of the trend of change, the contribution of intra-regional variation over the sample period showed a slightly increasing trend from 29.906% in 2012 to 30.172% in 2022, while the contribution of hyper-variable density showed a significant increasing trend from 25.534% in 2012 to 44.829% in 2022; The contribution rate of inter-regional differences shows a sharp downward trend from 44.560% in 2012 to 24.999% in 2022, which shows that the contribution rates of the current sources of spatial differentiation in the efficiency of rural industrial integration in China are, in order, hyper-variable density > inter-regional differences > intra-regional differences.
In 2016–2022, the distribution curve of three-dimensional kernel density in central China shows an overall trend of “two peaks”, with the main peak on the left and the secondary peak on the right, and the ductility of the main and secondary peaks shrinks, indicating that although there is still a trend of agglomeration in the efficiency of rural industrial integration in central China, the gap of the efficiency of rural industrial integration between central China’s regions has been narrowing, which contributes to the common development of rural industrial integration in central China.
As shown in Table 5 , on the whole, the combined efficiency and scale efficiency of rural industrial integration in the west show a decreasing trend, and the combined efficiency of rural industrial integration in the west decreases from 0.995 in 2012 to 0.968 in 2022, with a decrease rate of 2.771%; The scale efficiency of rural industrial integration in western China decreases from 0.996 in 2012 to 0.963 in 2022, with a decline rate of 3.256%; The pure technical efficiency of rural industrial integration in the west shows an increasing trend from 1.000 in 2012 to 1.005 in 2022, with a growth rate of 0.509%.