Barely Significant

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When \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$tau$$\end{document} tau >0, it indicates that the sample has an increasing trend; when \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$$tau$$\end{document} tau is negative, it indicates a decreasing trend.
Given that a previous study identified a near-significant association at the CFA10 locus in a case–control GWAS within the ACS breed 12 , we further investigated the genotypes at the CFA10 SNP in the present ACS population—85.7% of affected dogs were homozygous for the A allele compared to 62.5% of controls (Supplementary Table S1 ).
However, C org burial rate showed different trends along the sediment depth profile and across periods, tending to decrease from 12 cm depth towards 7 cm depth (comprising the period 1917—1951), shifted to an increasing trend between 7 cm depth and 3 cm depth (comprising the period between 1951 and 1978) and shifted to a decreasing trend again from 3 cm towards sediment surface (i.e., from 1978 towards present).
This could be attributed to the increasing demand for ready-to-eat (RTE) foods by many individuals, probably because minimal or no preparation is required before consumption as well as changing lifestyles 7 . Listeria monocytogenes (Lm) which causes listeriosis, is one of the leading pathogens that have been implicated in several foodborne outbreaks with an increasing trend of listeriosis since 2008 8 – 11 .