Excerpts

The molecular essence of all samples was consistent between measurements on the solariX and scimaX systems, with ANOVA revealing highly significant differences among sample groups ( p < 2 × 10 –16 ).

This leads to a highly significant coefficient ( β ˆ = 4.68 ; p<2e-16).

The dispersion parameter is clearly significant ( φ ˆ = 9.26 ; p<2e-16), indicating that there is strong evidence of overdispersion in the data that needs to be captured.

Phrase duration of female response songs differed highly significant among the five groups of females (ANOVA F 4,71 = 52.7, p = 2 × 10 −16 ).

When the DPPH activity of the extract and ascorbic acid were compared using an additional ANOVA test, the results showed a highly significant difference ( p -value < 2 × 10 −16 ).

t-PGCS DNMs and likely post-zygotic DNMs) we first fit a simple Poisson regression model that calculated the effect of paternal age on total autosomal DNM counts in the R statistical language (v3.5.1) as follows: glm(autosomal_dnms ~ dad_age, family = poisson(link='identity’)) This model returned a highly significant effect of paternal age on total DNM counts (1.72 DNMs per year of paternal age, p<2e-16), but was agnostic to the family from which each third-generation individual was ‘sampled.’ Importantly, a number of third-generation individuals in the CEPH/Utah cohort share grandparents, and may therefore be considered members of the same family, despite having unique second-generation parents ( Figure 3—figure supplement 1 ).

Specifically, adjusting for African ancestry in a multiple regression model largely eliminated the highly significant effect of Black ethnicity on serum creatinine levels (decreased from P<2x10 -16 to a marginally significant P=0.05) whilst the highly significant effect of African ancestry on creatinine remained essentially unchanged when adjusted for Black ethnicity (P<2x10 -16 before and after adjustment).

Statistical analysis via disk diffusion assays revealed highly significant differences in inhibition zone diameters among microorganisms ( p < 2 × 10 −16 ).

Smooth terms for latitude and longitude were highly significant (p < 2 × 10−16), further confirming the spatial structure of life expectancy outcomes.

We found highly significant differences ( p < 2 e - 16 ) between most cluster pairs at K = 5, except clusters 2 and 5 ( p ≈ 1 ) and clusters 2 and 3 ( p = 1.2 e - 09 ).

A model without interaction showed a highly significant effect of voxel on spectral quality ( Fig. 3 a ; F (1,79.12) = 183.73, p < 2 × 10 −16 ), with LO linewidth broader than EVC.

After including non-LA ω-6 PUFA in the model, the association of the FADS with LDL-c remains highly significant ( p < 2.0 × 10 −16 ).

Result After controlling for baseline age, sex, education, APOE ε4 dosage, and self‐reported race, IFI44L genotype strongly associated with clinical trajectories in clinically normal (CN) individuals and those with mild cognitive impairment (MCI) in the ADNI cohort, with the rs273259 alternate (G) allele displaying a highly significant, dose‐dependent relationship with worse clinical trajectories (for CDR‐SB, in CN, p < 2 x 10 ‐16 ; in MCI, p = 1.1 x 10 ‐6 ; Figure 1A‐B).

As expected, the PY effect was highly significant (P < 2 × 10 −16 ), and the smoking group W5Y remained significant after correcting for PY (P = 0.008).

We found a highly significant relationship between NPAS4 affinity scores and NPAS4 ChIP-seq peak intensity (mouse and rat P < 2 × 10 −16 , Supplementary Fig.

Overall, a log-rank test comparing survival across selection regimes revealed highly significant differences in lifespan (χ2 = 274, df = 3, p < 2e–16).

As for senior authorship, the difference between men and women was highly significant in both the 1999 (166 vs. 47, p = 2e-16), and in the 2009 cohort (188 vs. 115, p = 3e-5), but inspection of the absolute difference reveals that this difference is diminishing.

All p -values for the correlation coefficient are highly significant ( p -value < 2.0 × 10 −16 ).

The intersection is statistically highly significant (p < 2 -16 ).

Of these 316 genes, 81.5% (256) were found in our original list, a highly significant overlap ( P < 2 × 10 -16 , Fisher's exact test), demonstrating the reproducibility of our methodology.

found that incorporating more than 2000 PRSs to predict coronary artery disease, the increase in AUC ranged from 0.003 to 0.023 compared to a model without MPS, and the p-value for the increase in AUC were all highly significant ( p < 2e-16) 19 .

A highly significant difference in allelic frequencies was observed across all analyzed polymorphisms (chi-squared test, p < 2 −16 ).

All pairwise comparisons were highly significant ( p ‐value < 2e−16), indicating that the distribution of Tajima's D values differs between every pair of populations. 3 Results From the DNA extracted from the six toe pads, we sequenced between 135,310,794 and 208,948,341 Illumina pair reads per sample.

We obtained a highly significant interaction effect between hosts and isolates nested within each population for virulence (degrees of freedom = 1,540, F = 2.11, p < 2e −16 ) and reproduction (degrees of freedom = 1,540, F = 2.68, p < 2e −16 ).

Similarly, aphid counts and damage scores also showed a highly significant difference ( p -value = 2 × 10 −16 and 3.59 × 10 −14 ) ( Figure 6 C).