Barely Significant

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Patients with an SDI ≥4 showed significantly higher ICA-RI (0.70 (0.68–0.77, IQR) vs 0.67 (0.60–0.72, IQR); p=0.032), while differences in ICA-PI (1.34 (1.22–1.69, IQR) vs 1.19 (1.01–1.51, IQR); p=0.057) approached, but did not reach statistical significance. cIMT correlated with age (r=0.47, p<0.001), MAP (r=0.302, p<0.001) and long-term medication with statin (r=0.26, p<0.001) and showed an inverse association with estimated glomerular filtration rate (eGFR) (r=−0.202, p=0.011). cIMT was furthermore lower in patients with ENA-positivity than in those without detectable ENA (0.78 mm (0.69–0.9, IQR) vs 0.84 mm (0.74–0.95, IQR); p=0.012).
highly significantP < 0.0010.0× alphaqualifiedgold
The permuted multivariate analysis of variance (perMANOVA) with Aitchison distances to test the effect of the agricultural practices indicated a large and highly significant effect on the bacterial community that explained 45% of the total variance ( P < 0.001, Table 2 ).
almost significantlyp < 0.0010.0× alpha
Furthermore, we examined IL-6 which was diminished significantly by the LCPUFA combination, but almost significantly increased by EPA supplementation compared with LCPUFA-supplemented mice (Fig. 1d : IL-6: PBS: 93.25 ± 8.84 fg/mL, p < 0.001; HDM: 68791.00 ± 17601.00 fg/mL, LCPUFA: 27212.00 ± 7621.00 fg/mL, p < 0.05; EPA: 78843.00 ± 27842.00 fg/mL, p = 0.09).