Barely Significant

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highly significantP < 0.0010.0× alphaqualifiedgold
Cox regression analysis showed an upward trend in mean seasonal exposure rates amongst RSVH cases between 32 wGA (0.638) and 35 wGA (0.707) and the Wald statistic for seasonal exposure as a predictor of change in hazard for RSVH was highly significant ( P < 0.001) in every group.
highly significantp < 0.0010.0× alphaqualifiedgold
Compared to the Normal Control (NC) group, which exhibited basal physiological levels of these enzymes (MMP-1: 5.2±0.8 ng/mg protein; MMP-13: 3.9±0.6 ng/mg protein; ADAMTS-4: 2.3±0.4 ng/mg protein), the OA Control group displayed a highly significant (p < 0.001 for all) upregulation of MMP-1 (to 15.8±2.1 ng/mg protein, approximately a 3-fold increase), MMP-13 (to 12.5±1.7 ng/mg protein, approximately a 3.2-fold increase), and ADAMTS-4 (to 9.1±1.2 ng/mg protein, approximately a 3.95-fold increase).
highly significantp=0.0010.0× alphaqualifiedgold
Regarding external validity based on the relationship with another variable, we found that the overall score of the Collao Quechua WAST and the Patient Health Questionnaire (PHQ-9) show a direct, highly significant relationship and a moderate strength of relationship (Rho=0.618, p=0.001); this confirms external validity.
highly significantp<0.0010.0× alphaqualifiedgold
Among caregiver characteristics, highly significant and consistent associations were observed between poorer caregiver health, as measured by the SF-8, and three of the four measures of child health (OR, 1.68, p<0.001 for fair/poor health; OR 1.40, p<0.01 for illness in past 6 months; OR, 1.56, p<0.001 for persistent fair/poor health).
highly significantp < 0.0010.0× alphaqualifiedgold
We included seven HIV-1 integration site data sets for this analysis: two derived from this study (data sets of the same cell type combined; n = 1,484) and one other MDM data set (n = 754) and four other CD4 + T cell data sets (n = 4,613) obtained elsewhere 14 , 18 , 31 , 32 , 33 ( Table 2 ), By comparing the frequencies of HIV-1-hosting genes linked to clonal expansion of latently HIV-1-infected CD4 + T cells in gene hotspots and genes with single HIV-1 integration events, we observed a highly significant increase of genes linked to clonal expansion of latently HIV-1-infected CD4 + T cells in gene hotspots in CD4 + T cells (2.5×, p < 0.001), but not in MDMs ( Fig. 5b ), showing again that the repertoires of genes accessible to HIV-1 for integration in the two cell types were distinct.