Both the pro and active forms were present in wild-type mouse brain, but there was a highly significant conversion from the inactive to the active form in 5M P301S mice ( P < 0.001, one-way ANOVA) ( Fig. 6, A and B ).
Excerpts
Over 2000–2021, ice discharge in this sector shows a statistically highly significant ( p < 0.001) negative trend while OTF shows a statistically highly significant ( p < 0.001) positive trend until 2019 (Fig. 3 b).
For both song and ml noise, the difference in eBW between NRC and GLM STRFs was highly significant ( p<10 −3 , two-sample KS test).
Correspondingly, the week 1 difference in mean concentrations between groups was highly significant (p < 0.001).
The results of the multiple logistic regression analyses indicated a highly significant correlation between extinction and O 2 -carrying capacity ( p < 0.001; Figure 3 A; Tables S3–S9 ).
Total bilirubin, aspartate transaminase, and alanine transaminase in both groups showed a decreasing trend with time (time effect: F = 30.270, 17.340, and 13.380, respectively; all P < 0.001).
Two-way repeated measures analysis of variance (ANOVA) revealed a highly significant effect of group in male (F 3, 100 = 36.7; P < 0.001) and female rats (F 3, 100 = 34.8; P < 0.001).
VFA BIA and VAT CT ( r = 0.60, p < 0.001) showed moderately significant correlations in the total population and strong correlations in the gender-specific subgroup analysis (female r = 0.73; male r = 0.82; p < 0.001) (Fig. 3E, F ).
When the estimated missing effects were included in the analysis, the global association between adversity and psychosis remained highly significant, k = 45; OR = 2.29 (95% CI = 1.91–2.74), p < .001.
For testing for haplotypes and disease association, the chi-square value for haplotypes was 19.5-still highly significant ( p < 0.001).
The linear regression was found to be highly significant ( p < 0.001) for both models.
Figure 3f shows that totalPER increased in proportion to fivePER for the wildtype flies, yielding a highly significant effect (F(5, 443) = 201.54, p<.001, η 2 = .70).
The RET + KET group showed highly significant reductions in general alcohol consumption (beer, wine or spirits) from baseline to post manipulation [ F (1,89.17) = 19.55, p < 0.001, n p 2 = 0.14], equivalent to a reduction of 23.5 UK units/188 g ethanol over a week.
The pathways related to axon guidance, long term potentiation and arrhythmogenic right ventricular cardiomyopathy (ARVC) were highly significant (P<10 −3 ).
In our aforementioned study, the systematic inaccuracies revealed highly significant (F tests, p<0.001 for 6 out of 10 subjects).
Totally for all pair-wise comparisons of these homologous tissues, the average human-mouse difference was highly significant ( P <10 −3 ).
The pooled effect size verified that antioxidant supplementation exerts a highly significant, positive impact on increasing the number of high-quality embryos retrieved [MD = 1.08 (95%CI: 0.69–1.47), P < 0.001] ( Table 3 ; Figure 3C ). 3.4.4 Live birth Only 3 studies reported live birth rates.
The model remained highly significant ( P < 0.001) also when validated using a binary logistic regression model, as described in Methods.
This result was confirmed by the ML-HKA test [25] , for which a model allowing selection for PDS showed highly significant improvement to the likelihood compared with the neutral model (χ 2 = 19.62, df = 1, P <0.001).
showed a trendp < 0.001
The median overall survival in these patients receiving standard radiotherapy and concomitant temozolomide chemotherapy showed a trend towards better survival in group with methylated MGMT promoter (p < 0.001).
antidysenterica leaves at 100, 200, and 400 mg/kg/day showed 38.32, 64.49, and 76.64% parasitemia suppression, respectively; therefore, the differences in the results were highly significant ( p < 0.001) when compared with solvent-treated mice at day 4 (see Table 2 ). 3.4.
Nevertheless, in adulthood a significant trend towards decrease ( p < 0.001 in both sexes) was also observed, but food amount decreased significantly only in females.
Results of the construct validity assessment showed a highly significant difference (p < 0.001) between the CBAI scores obtained by two groups.
The inter-rater reliabilities between rater 1 and 2, rater 2 and 3, and rater 1 and 3 are highly significant (ICC = 0.998 to 0.999, p < 0.001).
Trend tests for the relationship between increasing pain intensities and increasing risk of LTSA was highly significant for all three body regions (P<0.001) (not shown in Table 2 ).