Barely Significant

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highly significantp < 0.0010.0× alphaqualifiedgold
Such extreme sample size heterogeneity and high data dispersion directly led to inconsistent subgroup results: no statistically significant differences were observed in either the HFrEF or HFmrEF subgroups (all p > 0.05), whereas a highly significant difference was detected in the HFpEF subgroup ( p < 0.001).
highly significantp < 0.0010.0× alphaqualifiedgold
The proposed model demonstrated highly significant improvements across all metrics ( p < 0.001), firmly establishing its robust predictive supremacy. 6.5 Robustness under noise and adversarial conditions Clinical environments frequently introduce image degradation due to poor sensor quality or inconsistent lighting.
a decreasing trendp < 0.0010.0× alphagold
In the segmented regression analysis by ICU patient-days, fentanyl presented with an increasing trend in use before the intervention (β = 16; 95%CI 7 - 25; p = 0.002), which decreased in level (β = - 128; 95%CI -195 - -62; p = 0.001) and then in slope for a decreasing trend (β = - 24; 95%CI -35 - -13; p < 0.001) ( Table 2 , Figure 2 ).
highly significantp < 0.0010.0× alphaqualifiedgold
Furthermore, comparison of IGF-1 between short-term survivors (1st quartile of time to death among deceased) and long-term (4th quartile of time to death among deceased) overall survival revealed a highly significant difference of IGF-1 levels (median IGF-1: 34.3 ng/mL vs. 54.8 ng/mL; p < 0.001).
highly significantP < .0010.0× alphaqualifiedgold
We also examined whether the prices paid by MA and commercial plans vary with hospital market concentration, as measured by the Herfindahl-Hirschman index (HHI). We found that the ratio of MA prices to Medicare FFS prices was not correlated with hospital market concentration (correlation = −.04; P = .06), but the ratio of commercial prices to Medicare FFS prices had a small positive and highly significant correlation with hospital market concentration (correlation = 0.19; P < .001) (see Online Appendix Figures 1 and 2 ).
highly significantp < 0.0010.0× alphaqualifiedgold
4.10 Clinical outcome As a result, in the patients' group, endothelial function improved as expressed by the highly significant increase in CFR during the RR session (p < 0.001) and after 60 days (p < 0.05) and a reduction (p < 0.05) of IMT in the carotid vessels after six months ( Fig. 7 ).