Barely Significant

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moderately significantp < 0.0010.0× alphaqualifiedgold
In addition, sICAM-1 had a weak correlation with TNF-α (rs = 0.392, p = 0.023), IL-6 (rs = 0.375, p < 0.001), and a moderately significant correlation with IL-8 (rs = 0.450, p < 0.001). sP-Selectins were weakly correlated with IL-6 (rs = 0.367, p < 0.001) and IL-8 (rs = 0.375, p = 0.013).
highly significantp value < 0.0010.0× alphaqualifiedgold
After adjusting for additional confounders (risk factors for both OUD and the outcome), the odds of diagnosis of each outcome decreased but remained highly significant: hyperthyroidism (AOR = 1.46, 95% CI 1.43–1.49, p value < 0.001), hypothyroidism (AOR = 1.45, 95% CI 1.42–1.48, p value < 0.001), type 2-diabetes (AOR = 1.28, 95% CI 1.26–1.29, p value < 0.001).
highly significantP < .0010.0× alphaqualifiedgold
Even fewer ADRs related to the anti-TNF therapy occurred in the intervention group after month 0, leading to a highly significant result favoring the intervention group (0.08 ± 0.10 vs 0.19 ± 0.19 [mean ± standard deviation] ADR/patient/month; P < .001; Figure 2B ).
highly significantP <0.0010.0× alphaqualifiedgold
Preterm labor was present in 48.2% of the cases as compared to 14.1% of the controls, and the difference was highly significant ( P <0.001). 54.7% mothers in the case group and 31.8% of the mothers in the control group had normal parturition, while other mothers delivered through a caesarean section.
highly significantp-values<0.0010.0× alphaqualifiedgold
In both Inuit men and women and among the Swedish fishermen the area of residence was of highly significant importance (all p-values<0.001) for the POP concentrations (Tables 5 and 6 ).