Results Analysis of phenotypic data Statistical analysis of plant architecture variables, obtained on the 266-pea-line collection at 8 and 14 days after sowing in Exp#1 and Exp#2, respectively, revealed highly significant G effects ( p-value < 0.001) for all the variables (Supplementary Table 1 ).
For all genes examined, induction was minimal and less significant in KO1 mice, whereas changes in KO3 and DKO mice were highly significant and of greater importance ( p ≤ 0.001).
At the 20 mm inter-tactor distance, we found a highly significant main effect of motor type on accuracy ( F (2, 32) = 27.99, p < 0.001, η G 2 = 0.24), but no interaction between the main effects of motor type and presentation direction ( F (2, 32) = 0.24, p = 0.788, for more, see results in “Tactile anisotropy”).
Comparing the log 2 fold changes in gene expression upon RA treatment with those upon 5-aza-dC treatment reveals a highly significant ( P < 0.001) positive correlation (R = 0.76, red), which is even retained when comparing those genes significantly regulated in only one of the two conditions (R = 0.72, 5-aza-dC, brown; R = 0.57, RA, green; Figure 1 C, left panel).
Safety comparison The ddTMZ+mEHT regimen did not display any grade II–IV toxicity, whereas the ddTMZ regimens generated such toxicity events at a rate of 45%–92%, the difference was always highly significant (p<0.001) ( table 9 ).
LVEF modifications with and without ablation In order to analyze the impact of CTIA on LVEF, we could show a highly significant impact of CTIA on LVEF in the ablation group ( n = 48) at 1 year (LVEF: 50.00 ± 20.00%; p < 0.001) and at 2 years (LVEF: 50.00 ± 20.00%; p < 0.001), respectively, compared with pre-intervention LVEF levels (LVEF: 35.00 ± 10.00%).
Using the same model as above (Model 1), a highly significant association between smoking status and mean cortical thickness was observed (F (2, 499)=14.7, P <0.001; Figure 2d ).
Assuming that other predictors were constant, the vertical diameter of the largest cyst at 300 μm predicted visual acuity loss with 62% sensitivity and 69% specificity with moderately significant predictive power (AUC=0.692; 95% CI=0.626-0.757; p<0.001, Figure 3b ).
Multiple comparisons Tuckey tests showed that there was a substantial increase in surface microhardness of the CESP group ( p < 0.05) and a highly significant increase ( p < 0.001) recorded by the UDD group when compared to the -ve CTL group.
The interaction term between fractions and total dose was highly significant and its interpretation is best understood by graphical representation of the model’s predicted outcome ( Fig 2D , p <0.001).