Excerpts

Association of TSR with Clinico-Pathological Features There is a highly significant correlation between TSR with luminal ER+ histological tumour type and grade (both p < 0.001), but not for TNBC.

As expected from earlier SAR work on this series, 6 , 7 , 8 there was a good overall correlation between the MABA and LORA MIC 90 values for the compounds: (1) l o g MABA = 0.98 ∗ l o g LORA - 0.08 n = 58 , R = 0.85 , p < 0.001 , F 2 , 56 = 144 Also, as expected, there was a reasonable correlation between inhibitory activity (illustrated here for MABA data) and compound lipophilicity, with the more lipophilic compounds being more potent; an overall trend repeatedly seen in other classes of TB drugs. 12 , 13 (2) logMABA = - 0.50 ∗ c l o g P + 1.97 n = 58 , R = 0.71 , P < 0.001 , F 2 , 56 = 55 However, this overall correlation masks a trend seen to some extent previously, 8 that for this general class of compound, MIC 90 potency falls off quite sharply for compounds (e.g., 3 , 8 , 16 , 18 , 23 , 25 , 27 , 29 , 31 , 42 , 44 , 52 ) of lower lipophilicity (clogP values around 4 or below).

Results with p < 0.01 were considered highly significant, and those with p < 0.001 were very highly significant.

Physio-biochemical attributes of wheat plants The influence of 80% and 50% FC on physiological and biochemical attributes of wheat was highly significant ( p < 0.001) for NAS and soil amended with different treatments, i.e., BAS, VCAS, PAS and ABAS as shown in Table 3 and 4 .

Chi squared for trend was highly significant (p<0.001).

This between-species difference is highly significant (p<0.001; t-test; N = 8, ambient temperature: 22–24°C).

Quantitative analysis confirmed a highly significant interaction between age and TZ size ( Fig. 2L ; ANOVA, F(4,18) = 298.03. p<0.001).

When adverse events were evaluated for the worst toxicity encountered during treatment, there was little difference between the groups, but when they were assessed per cycle, alternating treatment was associated with fewer severe (grade 3 or 4) adverse effects ( P = 0.013), and the difference was highly significant for cycles when gemcitabine was administered in group D/G ( P < 0.001).

Additionally, all variances of similarities were highly significant and were increased in FEBD (all p values< .001).

This difference approached significance using a paired t -test, p < 0.001 (Cohen’s d = 1.10).

The difference in occupancy rates in hunting versus non-hunting areas was highly significant (p<0.001) for all three species (t-tests assuming unequal variances were run for each species; Figure 2 ).

Data were considered statistically significant at P value ≤0.01 and highly significant at P < 0.001.

Age: A highly significant age effect was observed ( p < 0.001).

While in the latter these excess costs are still highly significant (€ 2,406.33, p <.001), they are largely reduced in those with lower SES (€ 538.62, p =.170; see also Figure 1.II.(b) (Fig. 1) ).

The standardized regression coefficient of the transformational psychological leadership style and organizational growth performance is 0.630, showing an extremely significant positive correlation ( p < 0.001).

The correlations between K xgI and 1/HOMA-IR and between K xgI and HOMA2 were positive and highly significant both in the whole sample (r = 0.565, P < 0.001 and r = 0.581, P < 0.001 respectively) and in the reduced sub-sample (r = 0.572, P < 0.001 and r = 0.558, P < 0.001 and respectively).

In this case, the chi-squared estimated values for the likelihood ratio, and Score and Wald statistics indicated that the model was highly significant ( p < 0.001).

There was a significant trend in average F-ECOHIS scores among those who attended for dental treatment, those attended for a routine dental check up and those attending for other reasons (P < 0.001).

For all of the laboratory-raised birds a DFA based on morphological variables was highly significant (Wilk's λ = 0.12, P<0.001) and correctly identified 100% of the individuals in a post-hoc classification based on a prior expectation of 50% correct classification by chance alone.

Independent of menopausal status, the difference in SI values between active and sedentary women was highly significant (p = 0.001), but that between sedentary and moderately active women was not (p = 0.065).

Out of 30 cases of invasive carcinomas of the breast, 28 cases were negative but only two cases showed weak positivity, i.e, DOG1 expression was positive in only 6.66% of cases of invasive breast disease which indicates that DOG1 expression in non-invasive lesions is statistically highly significant (p < 0.001).

Only the regression coefficients for nitrogen were highly significant (β = 1.20; t = 4.83; P<0.001).

Exercise was also shown to have a highly significant advantage over no therapy, in controls, to improve the negative symptoms in schizophrenic patients (–25 ± 8 vs. 0.2 ± 1.08, respectively; P <0.001).

The MTX‐treated group, as expected, demonstrated a highly significant reduction in paw edema, from 7.36 ± 0.35 to 3.54 ± 0.04 mL, which corresponds to a 51% reduction ( p < 0.001), confirming its effectiveness as a standard anti‐inflammatory drug.

Heart rate values were statistically highly significant lower in the labetalol group than magnesium sulfate group starting from intubation until 110 min after anesthesia induction ( p < 0.001), and both groups were comparable at baseline values ( p > 0.05) (Fig. 2 B).