At follow-up, the percentage of children receiving an antimalarial monotherapy in the intervention arm was lower than that in the control arm, although this was only of borderline significance in the adjusted analysis (difference in means: −10.5%: 95%CI: −3.9%, −16.9%; unadjusted p = 0.0036; adjusted p = 0.0518).
The association of AUC prednisone t 0-6 with Gd-IgA1 t 0-6 remained highly significant after adjustment for other immunosuppressants (p = 0.0036).
While smoking remained highly significant, both females (OR = 1.44, P = .0036) and Asians (versus Caucasians, OR = 2.49, P = .00060) were still significantly enriched in the EGFR -mutant group after adjusting for smoking status.
The gene-wise set test for the association of FMR1 with QIDS-SR was nominally significant with P=.0036, a probability which does not meet Bonferroni criteria for 36 genes tested (see Additional file 1 , sheet 2).
Highly Significant positive correlations were also found between SOC and total nitrogen ( p = 0.0036), total phosphorus ( p = 0.0006) and total potassium ( p < 0.0001).
This data was confirmed in A431 cells using flow cytometry showing a highly significant 4.5 fold increase in intracellular fluorescence (Fig. 2 ), P = 0.0036.
Using a Fisher’s exact test, it can be calculated that the distribution of proteins with altered versus non-altered protein amounts in the histone group (3 versus 4) was highly significant different from what could be expected among non-histone proteins (41 regulated and 830 non-altered non-histone proteins, p = 0.0036).
The difference between ICCA patients and control individuals was statistically highly significant (p = 0.0036 for ICCA.SRa and p = 0.0001 for ICCA.SRb, Mann-Whitney test; p = 0.0049 for ICCA.SRa and p = 0.0001 for ICCA.SRb, unpaired t-test with Welch's correction).
The differences between C1q-deficient and WT mice as well as between sIgM deficient and WT mice were highly significant ( P = 0.0036 and P = 0.0003, respectively).
Comparison of NGS and ddPCR results showed a highly significant correlation (ρ = 0.6047; p = 0.0036; Figure 5 A,B).
The use of the Fh16.5 protein generated a highly significant difference between the two groups (p value = 0.003614); as did enolase (p value was 0.02294).
As per Figure 2 , difference in mean proportion ranging 0.0-0.1% included highly significant penicllin and cephalosporin biosynthesis (p=3.69e −3 ) and significant-sulphur relay system (p=0.01), ascorbate and aldarate metabolism (0.02), polyaromatic hydrocarbon degradation (p=0.04), andpropanoate metabolism (p=0.04).
Preference for the rBNBl playback side was highly significant ( P =0.00369) ( Fig. 1 A).
Statistical modeling supports the following: the quadratic term of GG is highly significant, both without ATF ( p = 0.0037) and with ATF ( p = 0.0081), while AG-related and interaction terms remain non-significant.
The results were highly significant between N0/M0 versus N+ (p = 0.0037) as well as N0/M0 versus M+ (p = 0.0022) (Table 2 ).
We detected nominally significant enrichment for islet eQTLs for variants associated with continuous glycemic traits (normalized enrichment score (NES) = 1.27; P = 3.7 × 10 −3 ; Supplementary Fig. 9 and Supplementary Data 14 ): of all the tissues considered, islets generated the most significant enrichment for this phenotype.
The association between symptom duration and outcome was highly significant (χ2 = 11.18; df = 2; p = 0.0037), as demonstrated in Table 6 .
The effect on hind legs and quadriceps remained highly significant (Šidák corrected p ≤3.7x10 -3 ).
Similarly in linear regression, a highly significant relationship was seen when MCF7 cells were excluded from the analysis (Figure 5 ; p = 0.0037).
The ms/blink RT and the participants’ RT show a positive trend of longer reaction times for more memorized items, p = 0.0037 , p = 0.06 ( n.s. ) , and p = 0.00001 , respectively.
There was a highly significant difference between the two populations (3.6 % (27/747) and 8.6 % (19/222) in control and symptomatic dogs, respectively) ( P = 0.00379).
Overnight co-culture with progesterone (24 h) induced a highly significant reduction in NK cell cytotoxicity of tumor targets at differing concentrations (10 μM vs. 0.1 μM progesterone; n = 13; p = 0.0038; Figure 1 f).
Correlation among the serum DPP-4 activity, liver tests and HOMA2-IR in NAFLD Highly significant correlations were detected among the serum DPP-4 activity and ALT (r = 0.4637 p = 0.0038) and γGT (r = 0.4991, p = 0.0017) values in 39 patients with NAFLD.
The ANOVA of the Plackett-Burman design demonstrated that the model was highly significant as was evident from the Fisher’s F -test value of 23.55 with a very low probability value ( P -value = 0.0038) (Table 3 ) implies that the terms are significant.
We achieved a nominally significant signal only for rs11870474 at the ATP5H / KCTD2 locus (OR=1.43, 95% CI (1.12–1.83), P =0.0038).