Excerpts

Statistical analysis carried out on the timing errors, pooled over all subjects after averaging over all repetitions of each condition (four-way ANOVA, 3 [viewing distance] x 5 [ball descent duration] x 2 [figure type] x 6 [character type]), showed highly significant effects of character type ( F 5,1168 = 113.188, P <10 −7 ) and figure type ( static versus dynamic , F 1,1168 = 25.180, P <10 −6 ), less significant effects of viewing distance ( F 2,1168 = 3.602, P <0.05) and of the interaction between character type and figure type ( F 5,1168 = 2.569, P <0.05).

In this case, the first two PCs were highly significant, namely a Tracy-Widom test P-value <10 −7 , but the additional lower ranked PCs (third and onwards) had P-value larger than 0.05.

We found very strong evidence of association of multiple SNPs at TTC12 and ANKK1 in two different populations, EAs and AAs (minimal P=0.0007 in AAs and minimal P=0.00009 in EAs), and highly significant association of a single haplotype (set of markers) spanning TTC12 and ANKK1 to ND in the pooled sample (P=0. 0000001).

This positive coupling of both treatments was highly significant in a χ 2 -test of homogeneity ( χ 2 =29.6, degree of freedom=1, P <10 −7 ; Supplementary Table 5 ).

Ethnic Affiliation Related Pattern distributions differences in the various ethnic groups, which returned highly significant differences between the groups at the 5% level (χ 2 , p<0.0000001), have revealed that the Nilo-Saharan Berta manifested significantly higher Arch frequencies (18.68%), which is high both with respect to the other studied local ethnic groups (having arch frequencies less than 7%), as well as relative to other studied populations worldwide [ 3 , 4 ].

P i signal dropped faster than PCr increased during recovery (see Table 1 ); the correlation between the time constants τ PCr recovery and was highly significant ( r = 0.98, p < 10 − 7 ).

This is likely the case for many trans -eQTLs of marginal significance (5×10 −9 <P<10 −7 ), which are less likely to be cis -eQTLs than FDR-significant trans -eQTLs.

In a set of ubiquitously expressed housekeeping genes ( n =374), a highly significant positive correlation between expression and the mutational bias (B) (r=0.28; P <10−7) was reported 24 .

Statistical power drops off rapidly as the interaction odds ratio goes from 1.50–1.25; even at a modest significance level of P < 10 −7 , we did not have power to detect an interaction with an odds ratio of 1.25 for any condition ( Table S7 ).

Proteins that are part of the network show highly significant enrichment (all p-values <1e-7) in central cellular processes such as gene expression (GO:0010467), translation (GO:0006412), cellular localization (GO:0051641) and cell cycle (GO:0007049).

From duplicate measurements for each of three independent DNA preparations per construct, we again saw no effect of shRNA targeting Zfp423 , but a highly significant decrease on overexpression of human ZNF423 (p<10 −7 , Tukey HSD pair-wise test after one-factor ANOVA).

Regarding the favorability hypothesis, the combined effect of political climate was highly significant when the covariates were controlled ( Z = 6.68, p <.0000001) and when the covariates were not controlled ( Z = 6.45, p <.0000001).

As shown in Figure 4 A, a one-way ANOVA with 10 levels of Dream-Age (1–10 years) as independent variable and current (log) nightmare recall as dependent variable revealed a highly significant main effect ( F 9,17004 = 6.08, p < 0.0000001) showing that earlier recalled dreams were associated with frequent current nightmares.

Our work also provides a list of 28 genes that are highly significant (p<10 −7 ) in all the three M1 stimuli and could be used as a starting point to define an agreed global M1 signature, when validated with other M1-polarizing agents ( e . g .

The relationship between Cl and BW was also highly significant ( P = 10 –7 ), but the change in Cl as a function of BW is somewhat flat, as the PWR exponent was only 0.15.

Pearson correlations revealed low, but highly significant, positive correlations between DRF and DTD for the entire sample ( r 28888 = 0.282; p < 0.0000001) and for males ( r 5884 = 0.276; p < 0.0000001) and females ( r 23004 = 0.287; p < 0.0000001) considered separately.

flexneri was very highly significant ( P < 0.0000001), but survival of alone-cultivated A. castellanii compared to that of cocultivated with plasmid-cured S. flexneri was not statistically significant ( P = 0.88).

The coefficient for study arm was −12 (SEM 4.1), and the inclusion of study arm to the model was highly significant ( P = 10 −7 ), demonstrating a strong influence of the intervention on salt intake.

Using this metric, we see a strong positive ( r = 0.96 ) and highly significant (P < 10 − 7 ) Pearson correlation between the phylum and genus level predictions (see Tables 3 and 4 for this and other correlations).

Ingenuity Pathway Analysis of the VDR interactome revealed highly significant ( P ≤ 0.01 × 10 −5 ) enrichment of proteins involved in transcriptional repression and DNA methylation, as well as chromatin remodeling and gene silencing ( Fig. 6 F and Fig.

Interestingly, of these 117 genes a clear degradation effect was observed with 94 genes displaying preferential loss of a 3′ probeset and only 23 genes showing loss of a 5′ probeset suggesting highly significant (P < 1 × 10 −7 , repeat random sampling) 3′ degradation.

Genome-wide significance is generally considered any SNP with a p value less than 5 × 10 −8 ; however, SNPs reaching borderline significance, p < 10 −7 , will also be extracted as borderline significance has been found to be generally replicable [ 17 ].

There was a highly significant difference (P< 10-7) between the two groups of patients.

Only the mastectomy GWAS failed to yield nominally significant SNP hits ( P <10 −7 ).

Fisher’s exact tests further supported the differentiation in eight populations, indicating highly significant gene differentiation between all pairs of populations (P<10 −7 ).