Excerpts

However for responses evoked by octopamine and dopamine the correlation is high and highly significant (OA: r s = 0.93, p = 2e-7 [n = 24 responses from 6 oocytes]; DA: r s = 0.97, p = 2e-7 [n = 14 responses from 5 oocytes]).

Indeed, 69% of genes analyzed showed negative Z -scores in whole blood relative to other tissue types, which is highly significant ( p < 2 × 10 −7 , assuming a binomial distribution).

This is highly significant in EUR, when compared to the negative control regions, and modestly significant in ASN (<p = 2x10 -7 and p = 0.01 for EUR and ASN, respectively) and appears inconsistent with the null hypothesis of neutral evolution and demography at the LCT locus especially in the EUR populations.

This comparison revealed 56 common genes, representing a highly significant intersection ( Table S2 , P = 2E-07).

However, according to the Spearman rank correlation analysis the expression of IGF-IR and VEGFR-2 was highly positively correlated and statistically highly significant (r = 0.745 and p = 0.0000002) ( Figure 7 ).

Simple linear regression revealed a highly significant relationship ( p < 0.0000002) between road kill samples collected and rabid meso-carnivores detected in 2016 (r 2 = 0.86).

Mantoux test results were positive in 75.47% of cases and 24.53% of controls, and the difference was statistically highly significant ( P = 0.0000002).

Total between-groups Q, shown at the bottom of Table 8 (Q = 33.93, df(Q) = 3) indicates that there is a highly significant difference between the effectiveness of the four meditation categories on PTSD ( p < 0.0000002). 3.1.

While rs7041 only had a modest statistical association in our single-SNP GWAS ( p =2.8×10 −4 for antenatal and p =0.01 for cord blood), the results for haplotype association ( Table 4 ) were highly significant (ANOVA p =2.0×10 −7 for antenatal and p =3.0×10 −6 for cord blood).

There were 55 overlapping genes between these two datasets, a markedly significant enrichment (p < 2e-7).

Expectedly, their accumulation in the GRAS males yielded a highly significant Jonckheere–Terpstra trend ( P =0.0000002).

Lab values of included intervals ), mean baseline HIC and SF were not different (p < 0.7 and p < 0.2 respectively); overall, HIC and SF worsened during deferiprone treatment (p < 0.001 and p < 0.0003, respectively), and improved during deferasirox treatment (p < 0.001 and p < 0.0001, respectively); follow-up HIC values differing between deferiprone and deferasirox monotherapies were highly significant (p < 0.0000002).

Here we found clear differences between non-smokers (2.12 ± 2.07 μg/g creatinine) and smokers (411.37 ± 351.41 μg/g creatinine) that are highly significant (p = 2 × 10 −7 ).

In the HeLa cell line, BiP-MSR-3x had 53 times lower reporter activity than BiP-MSR-4x, a highly significant difference (Mann-Whitney U = 168, n1 = 14, n2 = 12, p < 2 × 10 −7 ).

In particular, we found a highly significant positive correlation between disease and the Magenta (comprised of 576 genes) module eigengene ( r = 0.67, P <2 × 10 -7 ), the Brown (2,502 genes) module eigengene ( r = 0.6, P <6 × 10 -6 ), the Light-Cyan (349 genes) module eigengene ( r = 0.42, P <0.002), and the Grey60 (based on 216 genes) module eigengene ( r = 0.47, P <8 × 10 -4 ).

When considered together, the 19 methylation biomarkers demonstrated exceptional predictive power, with an AUC of 0.95 and an accuracy of 0.88 at a highly significant P = 2.02e-07 ( Fig. 2 A ).

Among the 401 genes implicated in ID, we identified 106 genes coding for GRFs, which represents a highly significant enrichment of GRFs among all ID genes (hypergeometric test, p = 2.03 × 10 −07 ).

For the four higher concentrations, there are highly significant differences among groups (10 −2.5 F 3,76 = 14.145 *** p = 2.05 × 10 −7 ; 10 −2 F 3,76 = 60.371 ***, p = 4.56 × 10 −20 ; 10 −1.5 F 3,76 = 50.504 ***, p = 4.63 × 10 −18 ; 10 − 1 F 3,76 = 26.148 ***, p = 1.01 × 10 −11 ; *** = p < 0.001).

The effect of growth forms was insignificant in the Asteraceae and the Brassicaceae, possibly due to the limited number of non‐herbaceous species, but the effect was highly significant in the Solanaceae where non‐herbaceous species are abundant ( p = 2.078 × 10 −7 ).

All CpG sites, except one site (cg21161138) near AHRR , remained nominally significant (3.17 <| z |< 5.19, 1.52e − 03 < p < 2.10e − 07) with the same direction of association in the sensitivity analysis adjusted for smoking (Additional file 1: Table S1 and Fig.

The association between p57 negativity and CHMs was highly significant (χ 2 = 26.94, p = 2.1 × 10 −7 ; Fisher’s exact p < 2 × 10 −7 ).

While saliva sample volume remained the variable with the largest effect (P = 6.8x10 -27 ), DNA turbidity and purity where highly significant at P = 2.1×10 -7 and P = 1.8×10 -4 , respectively.

The cross-validated model was highly significant for the difference between matched case and control sample (p = 2.1*10 −7 ).

Polygenetic risk score (PRS) constructed by using three independent SNPs (rs1410996, rs4698775, and rs2043085) showed highly significant association with CSC ( p = 2.10 × 10 –7 ), with the top 10% of subjects with high PRS showing 6.39 times higher risk than the bottom 10% of subjects with lowest PRS.

Fisher’s exact test revealed a highly significant ( P = 2.13e−07) association between viruses in the species Magarnavirus gigas (proposed) and oysters with obvious signs of disease, when compared to naturalized beach oysters with no sign of disease.