Both changes in slope, before and after 1994 to 2002, were highly significant (p < 10 -6 in both cases).
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This association between essentiality and positive selection in the LTEE is highly significant (Fisher’s exact test: P < 10 −6 ).
Such a difference is highly significant ( p < 0.000001, Figure 5 a) and corresponds to a significant difference ( p = 0.02656) between the corresponding E distributions.
Differences between eukaryotes and bacteria, or between eukaryotes and the combined archaeal/bacterial data set, were highly significant ( P < 10 -6 that both represent samples drawn from the same population for each pairwise test). 5.
The differences between MS and control findings was highly significant (p > 0.000001).
Global analyses identified a total of 2,053 sites with overlapping peaks, and statistical analyses showed that this overlap is highly significant ( Figure 2 B) (p < 10 −6 , calculated using a permutation test with 1.0 × 10 6 iterations).
Significant differences were observed between the SIDS and non-SIDS groups: the presence of thymic petechiae in SIDS (89.5%) compared with non-SIDS (47.7%) was highly significant ( P < 0.000001; OR 9.38 (CL 4.5 to 19.9), and their absence was more frequent in non-SIDS (52.3%) compared with SIDS cases (10.4%) ( P < 0.000001).
Specifically, the group‐average correlation between condition‐specific performance and d’ was 0.97 (SEM = 0.06) and highly significant (T(18) = 32.57, p < 10 -6 ).
Bioinformatic screens for differential TACE mRNA expression using the Oncomine database ( www.oncomine.org ) confirmed the highly significant ( P <10 −6 ) increase in TACE transcript levels in HNSCC specimens ( Cromer et al , 2004 ).
Differences between populations accounted for only 6.96% of the variance, but was highly significant ( P < 1.0 * 10 −6 ).
Compared to eleven published inactive conformation structures bound to various antagonists, the widening of the pocket by more than 2 Å caused by WAY-196619 is highly significant (Student’s t-test, p< 1×10 -6 )( Figure 4a ).
We find a considerable fraction (~30%) of Pol III-occupied loci reside within CpG islands, a highly significant overlap (p-value<10 −6 ), and a striking correlation exists between Pol III occupancy and CpG content at Pol II promoters.
The differences in the SD values between the POST and PRE groups were highly significant, P < 10 -6 for TP53 and AML1 , and P < 10 -7 for CEN17 (Table 1 ).
6 a) shows similar performance between the NMF and PCA methods, with a small but highly significant trend towards increased values for the NMF method ( p < 10 − 6 , Wilcoxon Signed-Rank test).
We observed similar and highly significant shifts (p<.000001) to positive levels of coordination for both amygdala-cingulate and prefrontal cortex regions using MAS5-normalized data, as we did with GCRMA-normalized data (not shown).
As shown in Figure 3 , while reduction in binding after treatment with unlabeled DARPin 9_29 was highly significant ( p < 0.000001), there was neither significant reduction in binding after receptor saturation using trastuzumab ( p > 0.05) nor any reduction in binding after treatment of SKOV-3 cells with cetuximab or bevacizumab.
The observed enrichment (7 of 7) is highly significant (p-value = 1e-6), demonstrating that our serum proteomic analysis finds high concordance with validated assays.
Convergence was obtained for all morphological traits and in all cases the full model accounted for significantly more variance than the constants-only model and this difference was highly significant ( P < 10 −6 ).
Twenty-five additional independent loci showed moderately significant ( P < 1 × 10 −6 ) associations, nine with endometrial cancer overall, nine specifically with endometrioid histology, and seven with non-endometrioid histology (Supplementary Data 2 ).
The difference between the removal of the 5224 genes with high LEVs (improvement of interlaboratory correlation of 0.03) and random deletion of 5224 genes (mean increment of interlaboratory correlation of –0.00016) was highly significant ( P < 10 −6 ).
The behavioral phases of flies released at peak versus trough temperatures showed non-overlapping distributions with a highly significant difference (t-test P < 10 -6 ).
Both values are highly significant (p-value < 10 -6 ).
A strong, highly significant correlation between the frequency of tracking interruptions with the right and left hand was found (Pearson correlation, r = 0.834, p<10 −6 ).
The chi-square test for homogeneity of base frequencies across taxa was highly significant ( P < 0.000001 for all partitions examined, except with codon second positions P = 0.00926835), though the validity of this test is questionable because it does not take phylogenetic structure into account.
The expression profiles of highly significant differentially expressed genes [pvalue < 10 -6 with a FDR (False Discovery Rate) of 1.48. 10 -4 ; n = 292] have been categorized using hierarchical clustering.