Even after accounting for phylum identity, the clustering was still highly significant (PERMANOVA P < 10 −6 ).
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As expected, highly significant enrichment was observed in the mutant cells for ‘Wnt Receptor Signaling’ (p < 1e-6).
This file contains highly significant SNPs (P < 1 × 10 −6 ) from the mixed model analysis of the milk minerals and proteins.
For the EXP group, student test scores had increased at each stage of testing (post > pretest 2 > pretest 1), and the paired t tests at each stage were highly significant ( p < 10 −6 ).
Kolmogorov-Smirnov test showed this difference to be highly significant (p < 10 −6 ).
The difference, when tested by a likelihood ratio test, is highly significant (likelihood ratio chi-square = 931.0514, DF = 17, p < 0.000001).
Of the 134 network components, 65 (49%) show a significantly rhythmic mRNA expression profile in liver, a highly significant enrichment when compared to a random selection of genes from this expression data set (p<10 −6 ; Chi-squared test).
The analysis yielded several significant findings: Firstly, a highly significant main effect of enrichment was observed on CO 2 consumption efficiency [F(1, 14) = 275.84, p < 0.000001].
The difference between ASLs and ASELs means was highly significant ( p < 10 −6 ), and the variances were highly significant different ( p < 10 −6 ).
Similarly, the marital status distribution (35 single individuals out of 40 cases) showed a highly significant deviation from the expected proportion ( p = 0.000001), suggesting that single individuals are at notably higher risk.
Supplementary Materials Supplementary Table 1: nominally significant genome-wide significant findings with a P value < 1 × 10 −6 .
Convergence was obtained for all morphological traits and in all cases the full model accounted for significantly more variance than the constants-only model and this difference was highly significant ( P < 10 −6 ).
A Chi-square test of independence indicated a highly significant dependence ( p = 0.000001) between cell type and localization of the signal within the cell.
This highly significant difference (2.1-fold; P ≤ 10 −6 ) suggests that some of the low-scoring sites might be false positives of the ChIP approach and that the overall prediction performance might have been underestimated.
The differences found were highly significant related to group B vs group A (χ2 85,63 p <0.000001; O.R. 2,69 [2,16-3,34] )and related to group B vs group C (χ2 33,1 p < 0.000001; O.R 2,39 [1,75-3,26]).
A one-way repeated measures ANOVA confirms that the number of items had a highly significant effect on identification accuracy ( F (3,15) = 42.8, p <0.000001).
In Supplementary Data 6 , the association of CHRM3 activation with “urinary contraction” (literature ID 364) contains the p value and ROC AUC for “Urinary retention” and is classified as highly significant ( p ≤ 1e-06), with distance 1 (i.e., the significant PT and starting PT are connected via 1 intermediate in the network, via the shared HT).
When we analyzed the gene expression data set, this pathway was also enriched highly significant ( p < 10 −6 ).
The effect of the total fixation time advantage was highly significant ( p < 10 −6 ), ruling out this alternative explanation.
Consistent with the reduction in peripheral blood myeloid cells, the reduction in contribution from Kat6a E/E ;Kat6b E/E fetal liver cells to bone marrow CMPs, GMPs and MEPs was highly significant (all P <10 −6 ; Fig.
Finally, when correlation values were raised to c = -80% and c = +80% highly significant GC values were obtained (Figure 3A , c = -0.8, GC = 1.056, P < 1 × 10 -6 ; Figure 3E , c = 0.8, GC = 1.073, P < 1 × 10 -6 ).
Considering nominally significant SNPs associated with each trait with p < 1 × 10 −6 in either study, we find a strong, significant positive correlation (Pearson correlation = 0.92, p < 2.2 × 10 −16 ) between effect sizes in BioVU and ATLAS ( Figure 4 C).
A very highly significant increase of Ang‐2 concentration ( p < 0.000001) was observed in CSF of MA patient in comparison with CTRL subjects (Fig. 1A ).
3 Results 3.1 Evaluation of the Visual Screening Test as Early Reading Predictor 3.1.1 Correlations Between Percentile at the Visual Search Screening Test Performed in Kindergarten and Z‐Score of 3rd Grade Reading Efficiency Figure 3 displays the correlation for the full sample (gathering children assessed at 3, 4, and 5 years old and categorized in percentiles) which appeared highly significant (r = −0.24, p < 10−6, n = 494).
This difference was highly significant ( U -test, p < 0.000001).