71 Analysis of the HPS also assessed simvastatin efficacy in subjects with and without diabetes and showed an effect consistent with the full cohort; 72 that is, simvastatin produced highly significant reductions (22%; P < 0.0001) in the first event rate for major coronary events, strokes, and revascularizations in subjects with type 2 diabetes.
Excerpts
The log-rank test for the overall difference among the four survival curves was highly significant ( P < 0.0001), providing strong evidence against the null hypothesis of no difference in survival distributions between the CTI groups.
The analysis of the two-sample t -test has revealed significant deviations in run length, velocity, and off rate at higher and lower pH levels relative to the neutral pH of 6.9, with a highly significant probability ( p < 0.0001).
The mean serum CA-125 level was markedly elevated in the endometriosis group (51.9 ± 9.5 U/mL) compared to controls (16.0 ± 8.0 U/mL), showing a highly significant difference ( P < 0.0001).
Among neonates with AKI, when examining LOH as it relates to GA, we detected a significant trend: as gestational age increases, LOH decreases ( p < 0.0001; Fig. 2 ).
This at some points would also clarify how the statistics were computed exactly (e.g., "All subjects showed comparable difference and the difference in medians evaluated across subjects was highly significant (p<<0.0001).", p.10, is ambiguous to me).
Statistical analysis revealed a highly significant difference between the two groups (χ 2 = 23, P =0.0001).
Two-way ANOVA revealed highly significant main effects of both cell type (F 1,14 = 89.42, p < 0.0001) and ZnO concentration (F 3,14 = 11.00, p < 0.001), with no significant interaction effect (F 3,14 = 1.25, p = 0.326), indicating that the differential sensitivity pattern remains consistent across all tested concentrations.
Two-way repeated-measures ANOVA analysis showed an extremely significant effect of drug treatment ( F (4, 280) = 21.41, P < 0.0001) and trial effect ( F (7, 280) = 35.76, P < 0.0001).
Although there was no significant difference between the strains in the accumulation of mitochondrial point mutations in untreated cultures, upon irradiation, even at the lowest UV dose of 5 J/m 2 pol30-K164R cultures exhibited a highly significant ( p < 0.0001) increase of mitochondrial point mutations in relation to their POL30 + counterparts at the same dose (Fig. 3 c).
Statistical analysis of the IC 50 values for all essential PBPs demonstrated a highly significant reduction in drug affinity in the IS 48 clinical isolate compared with the ATCC 49175 reference strain ( p < 0.0001).
The mean CO efficiency in the mph1Δ strain was thus 0.20, a change that was highly significant when compared to WT (p<0.0001).
ANOVA revealed highly significant effects ( p < 0.0001) of experiment, genotype, and their interaction, indicating that genotypes responded differentially across years.
The model is highly significant (F-statistic p -value < 0.0001), and the RMSE values suggest reasonable predictive accuracy.
Boxplot analysis revealed highly significant differences between healthy individuals and stage IV patients ( P < 0.0001), as well as between stage III and stage IV groups ( P < 0.05) (Fig. 6 C).
The difference in survival between the two groups was highly significant (HR: 7.8, 95% CI: 4.0–15.2; p<0.0001) ( Fig. 2 ).
At PN50, the resulting blood Pb 2+ levels in these animals was 22.2±0.9 μg dl −1 ( n =47) for Pb 2+ exposed rats and 0.6±0.1 μg dl −1 ( n =64) for control rats, a difference that was highly significant ( P <0.0001).
These IHC results are in agreement with what was observed by Western blot (Figure 5 B), and statistical data analysis indicated the existence of a highly significant correlation between MBP-1 and HDAC1 expression in tumors (p<0.0001), with a Spearman rank correlation coefficient equal to 0.714 (Figure 6 A).
Table 2 (see PDF) shows a highly significant difference in vitamin D status between cases and controls (p < 0.0001).
Furthermore, the two-way ANOVA showed a highly significant interaction between CPS concentrations and UVB doses used in the experiment for both keratinocytes and fibroblasts ( P < 0.0001, Fig. 5 ).
The TPC model was highly significant ( p < 0.0001), confirming that the selected factors substantially influence extraction yield.
Twenty-four week-infected mice developed highly significant bone resorption relative to control mice in the maxilla palatal (0.65 v. 0.43 mm 2 ) ( P = 0.0001) and mandible lingual sides (0.80 v. 0.66 mm 2 ) ( P = 0.003) (Fig 1C and 1D ) of the jaw.
Results: In the present study, total 110 study subjects responded by completely filling out the questionnaire The total calorie and protein intake of the study subjects before and after giving intervention for three months was found to be highly significant (p-value < 0.0001).
ANOVA supported the quadratic RSM model for TAC (Table 3 ) with a highly significant model ( F = 27.21, p < 0.0001; R 2 ~ 0.96).
A decreasing trend was also found for NNRTI mutations, which dropped from 77.8% to 53.8% (p < .0001).