For example, the mean serum creatinine level fluctuates around 95 μmol/l throughout the whole study period, but there is a slight positive (ie, upward) linear trend for males above 75 years, while for women there is a slight negative linear trend for all age categories while the overall linear (very slightly positive) trend is nevertheless highly significant (p<0.0001).
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The difference between these groups was highly significant ( p < 0.0001), which underscores the substantial impact of modifiable clinical, psychological, and social determinants on brace-wearing behavior.
During perifusion of both the whole spinal cord and the cervico-trigeminal area, the interaction between the two factors of variation was found to be highly significant indeed (F 1-27 = 24.33 and F 1-22 = 30.17, respectively, p<0.0001; Table S1 ).
In addition to that, Cl demonstrated highly significant anti-inflammatory ( p < 0.0001) and anti-senescence ( p < 0.0001) effects.
Network events resulted in a highly significant positive shift in [Cl − ] i ( P < 0.0001, t -test, n = 75 network events from 16 neurons) and an acidic shift in pH i ( P < 0.0001, t -test, Figures 4A,B ).
Indeed, we found a highly significant correlation between latency and rise time ( n = 42, R 2 = 0.43; p < 0.0001) and rise and decay time ( n = 42, R 2 = 0.21; p = 0.002).
Migration assays revealed that both lyophilized and fresh PRF caused a highly significant ( p < 0.0001) 15- to 20-fold increase in the number of migrated cells when compared to DMEM medium ( Figure 2D ).
As shown in Figure 1 , levels of stool miR-221 ( Figure 1A ) as well as miR-18a ( Figure 1B ) displayed a significant trend of increase with lesion stages ( P <0.0001).
Note that extremely significant p = 0.0001 to 0.001 is shown with ∗∗∗, very significant p = 0.001 to 0.01 with ∗∗, and significant p = 0.01 to 0.05 with ∗.
The difference in survival between CN III and CN VI was statistically significant but modest ( p = 0.0012; HR = 1.074), while differences between CN IV and both CN III (HR = 0.42) and CN VI (HR = 0.419) were highly significant ( p < 0.0001).
Similarly, a short term reproductive success measurement of a seven day window in older females is highly significant ( P <0.0001) in predicting their lifetime reproductive success ( Fig 4 ).
Compared to both the healthy controls and the individuals with insulin resistance alone, patients with diabetes but without insulin resistance exhibited a highly significant upregulation (p<0.0001) in both their IL-10 mRNA levels within PBMCs and the corresponding IL-10 protein levels circulating in their serum.
We found that, within each scale at 10 h APF, a highly significant difference ( t test for two-independent samples; p < 0.0001) between actin-bundle areas was found.
Statistical analyses revealed highly significant differences between infected groups sampled at 12 h and 96 h for both genes ( p < 0.0001).
Statistical significance has been represented as extremely significant (****, p < 0.0001), extremely significant (***, p = 0.0001–0.001), very significant (**, p = 0.001–0.01), significant (*, p = 0.01–0.05) and not significant (ns, p ≥ 0.05). 3.
Upon HFD, the mice had a progressive body weight gain ( Figure 1 a), which was highly significant at 16 weeks ( P < 0.0001) ( Figure 1 b).
The influence both of cellular age and of radiation dose onto the number of micronuclei was highly significant (ANOVA test p < 0.0001).
The interaction between medium, forage and dose and the interaction between medium, forage and time were also both highly significant ( P < 0.0001). 4.
Statistical analysis results ( Table 3 ) Highly significant association resulted statistically for Plaque Urease / Gastric urease (chi-squared = 42.629), which correspond to (P<0.0001).
CCA indicated highly significant (p < 0.0001) time lags of 12 to 72 hours between i . the cyclic fluctuation of an elevated chlorophyll-a signal in the BBL and ii . signals from both the sea surface (occurrence of low atmospheric pressure, wave height (MWH), cooling of surface waters (SST) and the BBL (temperature, tidal signal (pressure), flow-velocity) during the period of investigation (November – May, Table 1 ).
Although we could not directly compare the miRNA quantification provided by a probe hybridization-based technology (Agilent microRNA microarray) and a digital PCR technology, we analyzed the correlation in microRNA quantification between these two approaches, after data normalization, and observed a highly significant correlation of the data ( p < 0.0001, Spearman r > 0.7) for all the tested cancer types.
The differences between groups A and B in the accumulated survival (Kaplan-Meier) were highly significant (log rank P value < 0.0001).
The difference in RWL between the 2 groups was highly significant (T-test: p<0.0001).
Highly significant ( P < 0.0001) decrease in fasting PG and 2 h PP-PG, HbA1c, ASL, ALT, fasting total cholesterol, LDL, TG, and increase in HDL were observed after bariatric surgery.
Specifically, there was a nominally significant increase in the proportion of neutrophils (beta = 0.025, p = 0.0001), and a decrease in the proportion of monocytes (beta = -0.007, p = 2.1e-6), CD8 + T cells (beta = -0.007, p = 0.025), and NK cells (beta = -0.009, p = 1.2e-5) (Table S3 ).