Barely Significant

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highly significantp < 0.00010.0× alphaqualifiedgold
Simultaneously, the results from Table 2 reveal that the individual factors A and D exert a highly significant influence on the response value ( p < 0.0001), while factors B and C exhibit a significant impact ( p < 0.05).
highly significantp < 0.00010.0× alphaqualifiedgold
Echocardiography The difference in Group I and Group II was highly significant in terms of both the baseline GLS (-13.37 ± 2.21 vs -19.11 ± 3.4; p < 0.0001) and GLS at 1-year follow-up (-11.23 ± 2.19 vs -13.47 ± 1.84; p < 0.0001).
highly significantP < 0.00010.0× alphaqualifiedgold
A significant increase in IgG immune response was observed in infected mice groups; specifically, the wild-type mice exhibited highly significant serum IgG response (>1,000-fold) to P. gingivalis ( P < 0.0001) and T. forsythia ( P < 0.0001), TLR2 -/- and TLR4 -/- mice showed significant IgG response to F. nucleatum ( P < 0.0001) and P. gingivalis ( P < 0.0001) (>90-fold), and TLR4 -/- mice had a robust level of IgG response to P. gingivalis ( P < 0.01) (>700-fold) ( Fig. 1D1–3 ).
extremely significantP -value ≤0.00010.0× alphaqualified
highly significantP -value ≤0.0010.0× alphaqualifiedgold
Statistical significance was defined as non-significant ( ns P -value >0.05), significant (* P -value ≤0.05), very significant (** P -value ≤0.01), highly significant (*** P -value ≤0.001), and extremely significant (**** P -value ≤0.0001).
highly significantp -value < 0.00010.0× alphaqualifiedgold
GradCAM which demonstrated that the sensitivity ( p -value < 0.0001 and p -value < 0.0001 respectively) was significantly different however specificity between HR-CAM and Zhou’s CAM did not vary ( p -value > 0.05) conversely between HR-CAM and GradCAM it was highly significant ( p -value < 0.0001).