Excerpts

Examination of patients’ clinical parameters showed that responders and non-responders presented highly significant differences in both progression-free survival (Fig. 1c , log-rank p < 0.0001) and overall survival (Fig. 1c , log-rank p < 0.0001).

This analysis confirmed a highly significant and selective match between mouse and human cerebral ependymoma but no other tested human brain tumor (permuted P <0.0001, Figure 4c ).

All differences turned out highly significant ( p < 0.0001).

There is a highly significant correlation between price volatility of the resource r in the EU, σ EU r , and TradeRisk (ρ = 0.71, P < 10 −4 ) (see Fig. 2A ).

Moreover, a negative correlation between TP and circulating CREA (ρ = −0.540; p = 0.004), which in turn markedly correlated with ALT and moderately with UREA in a negative and highly significant way [(ρ = −0.703; p < 0.0001) and (ρ = −0.560; p < 0.0001), respectively] was found.

Differences were considered significant when p < 0.05 (*) and highly significant when p < 0.0001 (**) versus each respective control or untreated control group. 2.7.

By contrast, there was a highly significant and strong effect of species ( R 2 = 0.5048, p < 0.0001), with pairwise tests indicating cranial shape differences between 16 of the 45 pairwise comparisons ( table 2 ).

No significant correlation was found with Dukes' stage (P= 0.15), but a highly significant correlation was obtained with DNA index > 1.30 (P<0.0001) as well as 17p loss (P< 0.002). p53 content was also significantly different when it was compared to tumour site (P<0.03), with a considerably reduced incidence in the proximal colon (42.1% positive cases) compared to an average of 74.8% in the distal seg- ments. r- U- 0 30 60 FL2 b 0 30 60 FL2 C 0 30 60 FL2 Figure 4 p53/DNA FCM results for a tumour of the rectum (DNA index 1.15).

In addition, analysis of transcriptome data from human pancreatic cancer samples using the Bailey RNAseq dataset [ 15 ] revealed strong positive and highly significant pairwise expression correlations of these platelet-regulated genes (Supplementary Fig. 2 C; p < 0.0001 for all correlations except for EFEMP1).

conventional FA concentrations in 2 tables, about 2 findings of P = 0.05 and 0.5 finding of P = 0.01 can be expected there by chance alone, but our key findings are highly significant ( P <0.0001) and not vulnerable to Type-I errors (incorrectly rejecting the null hypothesis).

This difference was highly significant, t(70.14) = 4.04, p = .0001 (degrees of freedom using Satterthwaite’s correction for unequal variance).

The quadratic equation so obtained presented a highly significant effect (p < 0.0001) of the solid lipid, surfactant concentration, and sonication time on the PS values.

In total, 2 of 15 transient lineages carry longitudinally persistent and induced prophages, while 9 of 9 persistent lineages carry such prophages, and a Fisher’s exact test indicates a highly significant association between inducible phage and persistence of lineage ( P < .0001).

The first principal component (PC1) accounted for 31.2% of the variance and showed a highly significant age trend (p<0.0001) with an r value of −0.55.

One-way ANOVA analysis indicated a highly significant difference of ictal/interictal-like discharges before and after carbenoxolone perfusion (F = 36.48, p < 0.0001).

After changing to a higher dialysate K, the decrease in plasma K concentration after dialysis remained highly significant: from 4.59 (4.35–4.80) to 3.77 (3.26–4.07) mEq/L (P < 0.0001) 1 week after switching and from 4.80 (4.58–5.12) to 3.70 (3.36–4.25) mEq/L (P < 0.0001) 2 weeks after switching.

Correlations ranged from 19% for male desiccation lt 50 (marginally non-significant) to 54% for female lt 100 (highly significant: P <0.0001).

The results from GLMMs model showed a highly significant relationship ( p < 0.0001) of both water temperature and light attenuation coefficient to Chl a concentration ( Figure 5 ).

There was a significant trend ( P < 0.0001) for progression of hepatic disease from fibrosis to cirrhosis and eventually to HCC with increasing age ( P < 0.0001).

Furthermore, there is a marked difference in the prevalence of preterm births, particularly in the unspecified preterm category, with PDA patients showing a prevalence of 76.24% compared to 58.31% among non-PDA patients, underscored by a highly significant P < 0.0001.

By day 30, the DG exhibited characteristic features of granule cell dispersion (GCD), with loosening of the granule cell layer, blurring of the boundary between the granule cell layer and molecular layer, and expansion of granule cell distribution ( Figure 1 C), in line with previous observations in experimental and human TLE [ 46 , 47 ].Quantitative evaluation of NeuN immunofluorescence demonstrated a highly significant, progressive increase across the evaluated longitudinal time points from day 1 to day 30 post-modeling (One-way ANOVA, F (4, 10) = 2495.0, p < 0.0001).

The permutation test confirmed a highly significant difference in the truncated SH sequences associated with both survival groups ( p < 0.0001).

The methylation differences between samples are highly significant (Wilcoxon rank test P < 0.0001).

We found a highly significant association between signal in the DCR6 and escape bias overall (main effect of phenotype p<0.0001, with significant within-genotype effects after controlling for multiple comparisons in CaSR +/+ and CaSR p190/p190 groups) ( Fig 4A ).

Activity Against Enterococci Directly after adding 50μg/ml IL-26 to Enterococcus faecalis ATCC 29212 cultures, an immediate and highly significant ( p ≤0.0001) reduction of the number of colony forming units (CFU) of approximately 98.4% was detected.