According to statistical evaluation with Fisher’s exact test of independence, the association between treatment with vaginal gel and overall improvement of cytological findings was highly significant when compared to the non-treated group ( p < 0.0001). 41 In the same study, the clearance of high-risk HPV was assessed to evaluate the efficacy of the vaginal gel.
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A one-way ANOVA revealed a highly significant effect of formulation on swelling (S w ) (F(7, 792) ≈ 43,176, p < 0.0001), with a very large effect size (η2 ≈ 0.997).
The BMD measured at the right first molar tooth within the alveolar bone showed a highly significant regression with age (brightness = 166.8 − 1.3 × age, r = 0.65, P < 0.0001).
The high variability between the lines was confirmed by highly significant values for the F test (F-value equal to 2.3 and 12.6, P < 0.0001 to ALS and PWM, respectively), for all genotypes, supporting the hypothesis that the AS population is representative for mapping resistance loci .
Statistical analysis using two-way ANOVA with Bonferroni post-test on a pairwise comparison of the profile of the unfertilized oocyte with mRNA profiles collected at different time points after fertilization revealed that the correlation between segment and mRNA level is extremely significant ( P < 0.0001), but that there is no effect of fertilization and time following fertilization ( P ≈ 1).
The models highlighted below were all highly significant ( p < 0.0001).
This compares well with the finding of Bala et al ., in which seroprevalence of syphilis was reported to be 1.2%[ 11 ] while the overall seroprevalence of syphilis in a study from Maharashtra was found to be 0.7% (90/13,008).[ 12 ] In our study, we found that seroprevalence of syphilis by VDRL test among male patients was 5.02 (365/7278) while that in females was 0.74 (368/50,030), and the difference between the two was highly significant.( P < 0.0001) It is comparable to the report by Geusau et al .[ 13 ] Moreover, in a study conducted by Tankhiwale and Naikwade, the seroprevalence of syphilis in males and females was 1.73% (44 of 2537) and 0.4% (46 of 10414), respectively.[ 12 ] The higher seroprevalence of syphilis in males could be because of the fact that only the suspected patients or high-risk patients or patients attending STI clinic are usually tested for syphilis serology.
However, only one locus pair (STR One8 and SNP One_U1012_68 ) showed strong evidence of being physically linked, with highly significant tests ( p < 0.0001) for departure from linkage equilibrium in each sample year.
GWAS p -values and R 2 effects were extracted and QTL selection criteria was carried-out based on standard conditions of significance: “highly significant” refers to P < 0.0001 and “significant” refers to P < 0.001.
The difference in the TCT of both orange peeling and suturing between sessions 1, 5, and 10 was highly significant ( P < .0001) ( Table 1 ).
MMP-8 levels also showed an increasing trend ( P < 0.0001) with increasing pack-year category, although no trend was seen with MMP-9 levels (Additional file 4 ).
Significant (>0.0001 P <0.05) and highly significant ( P <0.0001) deviations are shown with single and double asterisks, respectively.
Similarly, higher (∼1.8x) pTau181 and lower (∼0.7x) Tau levels were significantly (p<0.05) observed in ALS versus control samples and higher (mean=20.2) pTau181:Tau ratios achieved a markedly significant (p<0.0001) differentiation of ALS from controls.
Although not entirely valid, given the informality of the study, it is nevertheless interesting to note that this difference was highly significant (Chi square p < 0.0001).
Kaplan–Meier survival curves for all groups were compared using a log-rank (Mantel–Cox) test, which revealed a highly significant difference among treatments (χ 2 = 73.94, df = 7, p < 0.0001).
albopictus ), with statistical analysis (permutation test in MorphoJ) indicating highly significant differences between most of these species ( p < 0.0001; p < 0.01; and p < 0.05; S2 Table ).
The chi-square test for the contrast estimate was highly significant ( P < 0.0001).
Specifically, the Na, Tb, Alb, age, and Cr showed highly significant associations with survival (p < 0.0001 for Na, p = 0.0055 for Tb, p = 0.00016 for Alb, p < 0.0001 for age, and p = 0.036 for Cr).
This difference was highly significant ( P < 0.0001) in the case of TLR-9 stimulation and trended towards significance ( P < 0.06) in the case of TLR7 stimulation.
This represents an almost five-times enrichment for the presence of the AAAUAA motif in this set of highly expressed transcripts for storage proteins (which is highly significant, with p < 0.0001, according to the one-sided Fisher’s exact test based on a 2 × 2 contingency table) with respect to transcripts not involved in the nutrient reservoir activity (represented by a random sample of 6258 protein-coding genes whose 3′ UTR sequence is identified in rice, which showed a presence of the motif in about 20% of the 3′ UTR sequence).
Nominally significant MetaXcan results ( p < 10 −4 ) were investigated using gene set enrichment analysis. 2.8 Look‐Up of Results From Prior WL in COPD GWAS We compared significant results from our prior GWAS of WL in COPD [ 9 ] with results from the current analyses.
The correlation was highly significant (Spearman’s ρ = 0.74, p < 0.0001) and comparable to that between immunogenicity and MHC complex stability.
Model 2 Results Model 2 is given by: 4 q it = - 9.7530 2.5982 + 0.0072 0.0003 t + 0.9197 0.0015 q i t - 1 + 0.0501 0.0024 W i t - 1 + 0.0267 0.0041 e Lat i + 38.2003 10.6452 e Long i - 1.1578 0.2894 L a t i + 2.9320 1.0856 Long i + 2.9204 0.6886 ln Lat i + 15.8138 4.8442 ln - Long i + 0.1297 0.0259 L a t i · Long i + 0.0614 0.0278 d p t + 0.0337 0.0248 d p t - 1 + 0.0616 0.0261 d p t - 3 + 0.0043 0.0003 F I i - 4 The coefficient on the deterministic trend, 0.0072, was highly significant ( p < 0.0001), though somewhat smaller than that on initial month of production in Eq. 1 .
This pattern was again highly significant (r = 0.770, r 2 = 0.593, p < 0.0001).
Haematological Parameters Comparing infected and non-infected tilapias, the infected tilapias show a highly significant increase in white blood cells count compared to non-infected ones ( p < 0.0001).