Excerpts

This difference is highly significant (p = 0.0002, chi-square test). 4.

The PCR product size of ECR near HMX1 (duplication of 76 bp) showed a highly significant association with ear size in Awassi sheep ( p < 0.0002), in addition to the significant difference ( p < 0.001) between affected animals (earless versus short ear) ( Table 3 ). 3.6.

Results Participants characteristics The PIR exhibited a highly significant correlation with the risk of DR ( P = 0.0002).

However, we did find a highly significant increase in the rare/common CNV ratio in the LFS patients carrying mutations in the TP53 DBD when compared to both controls (p=0.0002) and to patients carrying the p.R337H mutation (p=0.0156; Fisher-exact test) (Figure 1B ).

A highly significant (p = 0.0002) effect on carcass weight was found for haplotypes detected on BTA12.

Applying repeated measures of variance methodology, a highly significant difference could be seen (F(1, 204) = 14.3; p = 0.0002) ( Figure 2 ), where those on active treatment exhibited higher e-GFR as a result of the treatment.

The median plaque score difference on the 100 th day between the two groups was highly significant (p ≤0.0002).

The difference between the cells infected with TTSuV1 and cells transfected with the unrelated DNA was highly significant at p = 0.0002 ( Fig. 2 ).

For overrun, sodium alginate (A) and Rügen chalk (B) exhibited highly significant effects ( p = 0.0002 and p = 0.0017, respectively).

This meta-analysis failed to show any benefits of adjuvant bisphosphonates in premenopausal women, but highly significant improvements in bone recurrence (RR = 0.72; 95% CI 0.60–0.86, 2 p = 0.0002) and breast cancer mortality (RR = 0.82; 95% CI 0.73–0.93, 2 p = 0.002) were seen in the 11,767 postmenopausal women included in the meta-analysis.

We find that there is a highly significant correlation between carrier status weighted by either acetylcholine EC 50 (β = −0.67, r 2 = 0.017, P = 2×10 −4 ) or by response to low nicotine (β = −0.29, r 2 = 0.02, P = 6×10 −5 ) when variants are expressed with the α3 subunit.

vivax infections (23–79%) was highly significant ( P = 0.0002), as was the variation in mean MOI (1.23–1.90); P = 0.0002.

Moreover, linear regression analysis indeed indicated a highly significant (p = 0.0002) positive correlation between O -GlcNAc level and Akt phosphorylation in cervical tissues (Fig. 5 b).

By day 3, the deficit was large and highly significant (sh-NC 2.21 ± 0.07 vs. sh-KCNN4 1.60 ± 0.13; mean difference 0.60 [95% CI 0.40–0.81]; adjusted P = 0.0002).These findings demonstrate a time-dependent and quantitatively large suppression of PC-9 proliferation following KCNN4 knockdown.

The correlation between the clock time estimate and clock time setting deviations was highly significant ( r =−0.88, p < 0.0002).

This analysis showed a highly significant difference ( p = 0.0002), highlighting that fistulectomy improves the quality of postoperative evacuations by promoting more formed and regular stools than fistulotomy.

Comparing the mRNA levels of tissue samples obtained from the dorsal horn of control animals and from the dorsal horn of CFA-injected animals ipsilateral to the CFA injection at post-injection day 3 (at the peak of mechanical allodynia), we observed a highly significant, approximately six times increase in the IL-1R1 mRNA ( p = 0.0002) in the experimental animals (Table 2 ).

Lastly, distant metastases were found to be a highly significant predictor of mortality among patients with multiple recurrences of WDTC ( P = .0002).

Moreover, a statistically significant ( P < 0.004) interaction between the organ sampling-time and the SNP treatment was revealed in kidney regardless of the dosing time, whereas a highly significant ( P < 0.0002) interaction was validated in liver only in animals injected at 13 HALO. pmc-status-qastatus 0 pmc-status-live yes pmc-status-embargo no pmc-status-released yes pmc-prop-open-access yes pmc-prop-olf no pmc-prop-manuscript no pmc-prop-legally-suppressed no pmc-prop-has-pdf yes pmc-prop-has-supplement no pmc-prop-pdf-only no pmc-prop-suppress-copyright no pmc-prop-is-real-version no pmc-prop-is-scanned-article no pmc-prop-preprint no pmc-prop-in-epmc yes pmc-license-ref CC BY 1.

For risk groups, a highly significant (likelihood ratio test p = 0.0002) Cox proportional-hazards model included statistically significant covariates age (HR 1.1 (1.0 − 1.2) p = 0.004), stage IV (HR 173.8 (9.1 − 3325.5) p = 0.0006), and invasive ductal (ICD-0-3 code 8500/3) histologic type (HR 0.06 (0.006 − 0.68) p = 0.023).

Indeed there is a highly significant correlation between urinary glucose and the glucose tolerance test area under the curve (r=0.623, p=0.0002), a measure of insulin resistance not directly influenced by food intake.

Quantitative analysis of RT-qPCR data revealed that, in breast cancer (BC) samples relative to control samples, PGR exhibited a 0.649-fold expression change with a non-significant difference (p = 0.0599); CD14 showed a 0.459-fold reduction with a highly significant difference (p = 0.0002); PPARG displayed a 0.480-fold downregulation with a significant difference (p = 0.0012); CHRM1 presented a 0.515-fold decrease with a significant difference (p = 0.0034); and HTR3A had a negligible 1.026-fold expression alteration with no statistical significance (p = 0.1223).

The enrichment for Cys-proximal N-linked glycosylation at the bases of the hyper-variable loops is highly significant (6/8 vs 0/16, p = 0.0002).

Apparent survival The U-CARE goodness of fit global test was highly significant (χ 2 = 36.93, d.f. = 12, p = 0.0002).

WGCNA highlighted a highly significant “turquoise” module comprising 78 downregulated genes ( P = 2e − 04).