Excerpts

Whereas the differences between S-HD, and both C-HD and HV-HDF were highly significant ( P < 0.0005), C-HD and HV-HDF were comparable in this respect ( P = 0.40).

All comparisons between targets were highly significant ( post-hoc , p < 0.0005).

First, all independent factors plus an interaction between norm violation and temporal order yield Pearson (χ 2 = 46.441; p = 0.224) and Cox & Snell = 0.490 with all factors highly significant, p < 0.0005.

All terms except FIP3 and FIP4 were highly significant ( P <0.0005) with FIC explaining 66.6% of the variation.

The results of two non-RCTs were additionally combined in an individual patient data meta-analysis, and showed highly significant results (HR: 0.43, 95% CI: 0.34–0.56, p < 0.0005) [ 135 ].

Both the 300IR and 500IR groups had highly significant improvements in Rhinoconjunctivitis Total Symptom Score (RTSS) vs. placebo at the peak pollen season ( P =0.0005 and 0.0014, respectively), which agreed with improvements in RTSS in the primary evaluations.

The differences between the three subgroups were indeed more pronounced when considering only children over the age of one year: subgroup α contained 89% of the UM and 79% of the SNCM patients but only 11% of the CM patients, whereas 78% of CM patients were found in subgroup β ( figure 4b ), and the association with clinical status was highly significant for both (p = 0.0005 and 0.0004, respectively).

The differences were highly significant (χ 2 (2) = 23.42, p < 0.0005).

Additionally markers on chromosomes 5, 10, 14, 15, 17, 21 and 24 had P values approaching significance (p≤5E-4).

Similarly, in univariate analysis, resistin showed a highly significant correlation with Lequesne index (PCC 0.324, p = 0.0005) that was markedly reduced after adjustment by confounders.

Regarding stage group, our study out of 36 resected cases revealed that combined MSH6 & PMS2 loss prevalent in stage III tumors (54.5%), followed by stage II tumors (45.5%), with a highly significant correlation combined markers loss between and III/II stages (p=0.0005).

Nature of employment and statistical topic were highly significant predictors of choice of the practice of statistics as a required competency ((F = 3.777, p < 0.0005) and (F = 45.834, p < 0.0005), respectively).

These titers exceed by >1 log the highest titers detected by earlier assay methods (29-31), and the difference between the seropositive patients and normal controls was highly significant (p < 0.0005).

Similarly, carotenoid content (CAR) exhibited a highly significant positive correlation with biological yield (BY) (r = 0.8447, p = 0.0005*) and TGW (r = 0.7378, p = 0.0062*).

divergens ( P = 0.002), and extremely significant for C. maltaromaticum and L. gelidum subsp. gasicomitatum ( P = 0.0005; P = 0.0005), respectively.

In all figures, we marked the permutation test results as follows: If the number of failures was, for example, 1 in 10,000 ( p = 0.0001) or less, it was marked as highly significant (***), 5 in 10,000 ( p = 0.0005) or less, as significant (**), and 10 in 10,000 ( p = 0.001) or less, as weakly significant (*).

The difference in the estimated proportions of homicide recidivists between published and unpublished data was highly significant (Q-value = 19.5, df = 1, p < 0.0005).

In comparing the percentage of responses between “currently” and “once adapted”, there was a positive trend in all of the % agrees, and a negative trend in all of the % disagrees (p<0.0005).

For the non-classical CD14 + CD16 ++ subset all the patients strongly showed this inverse relationship with Spearman’s rank correlation coefficient analysis showing this to be highly significant ( p ≤ 0.0005, Fig. 6 d–f).

Across nearly all cell types most of these P < 0.00001 genes had patterns consistent with specific expression in the correct cell types ( Figure 5 a), representing in all cases a highly significant enrichment relative to randomly selected genes (chi-squared P < 0.0005 to 10 −24 ).

Two immunizations of adjuvant-free or alum-emulsified immunogens consistently induced highly significant ( P < 0.0005-< 0.0001) reductions in the challenge worm burden.

Pairwise comparison of distances between individuals obtained from the probabilities of posterior assignment of population membership of individuals resulting from all five grouping methods ( Table 4 ) revealed highly significant correlations (p < 0.0005, based on 2000 permutations) in all cases.

Moreover, we observed a highly significant association between the expression of CCR5 prior to infection in a given subset and the percentage of cells infected ( p = 0.0005, Fig. 4 d).

A highly significant (p < 0.0005) decrease in pain threshold tolerance at the level of tenderness on skin rolling was found in comparison to non-tender control points in the thoracic spine [ 42 ].

The ANOVA results for tensile strength indicate that the quadratic model is highly significant (Model F = 35.51, p = 0.0005).