Interestingly, the nonsurvivors receiving appropriate empirical antibiotics showed a trend of no or less increase in Oxa-51 DNA compared with those receiving inappropriate empirical antibiotics ( P <0.001, Mann-Whitney U test, two tailed) (left panels, Figures 3B and 3C ).
After adjusting for baseline demographics, hospital characteristics, and comorbidities, we observed an increasing trend in the proportion of patients hospitalized with NSTEMI from 2002 to 2011 (adjusted OR [per year], 1.055; 95% CI, 1.054 to 1.056; P <0.001; Figure 1 ; Table 2 ).
GR demonstrated a highly significant association (p < 0.001) with the time-to-event outcome, suggesting that higher GR values are associated with a shorter time to response, with a hazard ratio of 0.575 (95% CI: 0.489 - 0.677), indicating a 42.5% reduction in the hazard rate per unit increase.
The mean reduction in office blood pressure was 14.1 mm Hg with active therapy and 11.7 mm Hg with placebo at 6 months, and was highly significant for both groups compared to baseline ( P <0.001), but the between-group difference was small (2.4 mm Hg) and not significant ( P =0.26).
Differences was considered statistically significant if P < 0.01 and highly significant if P < 0.001.
The mean postoperative refractive SE when implanting a plus power IOLs was −0.3 ± 0.51 D ( P < 0.001) while the mean postoperative refractive SE when implanting a minus power IOLs was +1.21 ± 0.11 D denoting a highly significant tendency toward hyperopia ( P < 0.001).
Figure 2 depicts the effect of different surface treatment (air abrasive and heat treatment) on the fracture strength of commercially available Ceramill (AMANNGIRRBACH) Zirconia, the result shows highly significant ( P <0.001) in the group 2, 3, 4, 5, 7, 8, 9, 10 and statistically significant ( P <0.005) in the group 6.
p < 0.05 was considered statistically significant, very significant if 0.001 < p < 0.01 and extremely significant if p < 0.001.
The use of vein grafts appeared to be a highly significant risk for a complete flap failure (p<0.001).
3.4 Population genomic analyses For each RAD dataset, all pairwise comparisons of genetic differentiation ( F ST ) between clusters identified in STRUCTURE and AWCLUST were highly significant ( p ‐value <0.001).
In normoxic conditions the inhibitory effect of all 5 compounds on cell proliferation in this cell line was highly significant ( P < 0.001) at 30 and 100 μM except for FC9396A which was significant at 100 μM alone and for FC9403 which significantly inhibited cell proliferation at 10 μM (Figure 1B ).
2 , Table 2 ; Adjusted R 2 = 0.4), although taxonomic level was highly significant in predicting divergence ( p < 0.001).
Food quality also had a highly significant effect on the probability of fighter expression given the effect of QTIW (LRT: χ 2 = 44.49, df = 4, p < .001), showing a plastic body size threshold that scaled with food quality (Figure 3a–f ). 4.
cerasoides ) was highly significant ( P < 0.001) in each case when compared to controls (number of animals in each group ranged from 7 to 10). 12.
The decrease in intrafollicular 17beta-estradiol concentration after the LH surge was highly significant (p < 0.001).
The combination of PQR620 with venetoclax showed highly significant differences either versus control or single agents during all days of the experiment (D4, D7, D9, D11, D14; p < 0.001), resulting in an eradication of the implanted tumors in the absence of toxicity.
Results The absorbed dose response correlation was highly significant ( R = 0.72, P < 0.001).
The mixed-model ANOVA revealed highly significant main effects of season ( p < 0.001, p 2 = 0.207) and treatment ( p < 0.001, p 2 = 0.109) on the plant colorimetric index, whereas species had no significant effect ( p = 0.210).
All step responses showed a strong effect of time with highly significant differences for the time intervals T1-T3 (Fig. 2 and Table 2 , all p < 0.001).
The results of the multiple regression hierarchy showed that the joint impact of gender and age with regards to being healthy or unhealthy only explained 2.7% of the total variance (adjusted R2), although the equation is clearly significant (F 2,320 = 96.3, p < 0.001).
Of the individual index components using score-specific cut-offs, the KPS was the most highly significant, showing the best discrimination amongst component levels ( p < 0.001) (Additional file 4 : Figure S2).
Aflapin supplementation for 30 days afforded highly significant (p<0.001) reductions in all the pain scores exhibiting 49.1, 34.4, 49.5, 48.4 and 45.2 percent reduction, in VAS, LFI, WOMAC pain, WOMAC stiffness and WOMAC function scores, respectively, when compared to the baseline.
A highly significant correlation between AREG and EREG mRNA expression was observed (Spearman ρ 2 = 0.736, p<0.001 ).
For OS, a highly significant correlation was revealed between high MMP-14 expression level and poor prognosis (HR = 2.2, P <0.001) (Figure 4 A).
On the other hand, in a sub-analysis on arterial and venous thrombotic events, previous thrombosis was a highly significant ( P <0.001) predictor of incidence of arterial thrombosis, but not of venous.