Barely Significant

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highly significantp ≤ 0.0010.0× alphaqualifiedgold
From the table, it appeared that highly significant difference (p ≤ 0.001) was found in diabetic group (G2) (10765 ± 1588.3 pg/ml), and cardiovascular, diabetic group (G3) (14421 ± 3411.6 pg/ml) as compared with the control group (G1) (7140 ± 619.8 pg/ml), also highly significant difference was appeared in G3 as compared with G2 ( Fig. 1, B ).
highly significantp < 0.0010.0× alphaqualifiedgold
Before interventions, the experimental group presents higher stiffness (0.49 ± 0.09, 0.60 ± 0.08, 0.96 ± 0.08 Nm/°) under different dorsiflexion angle level (0°, 10°, and 20°) than the control group pre-interventions (0.24 ± 0.06, 0.42 ± 0.09, 0.57 ± 0.09 Nm/°) due to ankle spasticity, and the differences are highly significant ( p < 0.001, p < 0.01, and p < 0.001).
highly significantp < 0.0010.0× alphaqualifiedgold
4.10 Clinical outcome As a result, in the patients' group, endothelial function improved as expressed by the highly significant increase in CFR during the RR session (p < 0.001) and after 60 days (p < 0.05) and a reduction (p < 0.05) of IMT in the carotid vessels after six months ( Fig. 7 ).
highly significantp < 0.0010.0× alphaqualifiedgold
Quantitative analysis revealed highly significant differences in spermidine levels between OIPN and CONT groups across all nutritional strata: in the whole cohort ( Figure 3F , p < 0.001), the malnutrition group ( Figure 3G , p < 0.001), and the well-nourished group ( Figure 3H , p < 0.001).
highly significantP <0.0010.0× alphaqualifiedgold
With a median follow-up of 20.7 months, this translated into a highly significant improvement of progression-free survival (median 13.8 vs. 3.6 months; hazard ratio=0.40 [95% confidence interval: 0.28-0.57]; P <0.001) and overall survival (median 25.5 vs. 12.9 months; hazard ratio=0.62 [95% confidence interval: 0.43-0.88]; P =0.006).