“a clear trend”

25) Although the data on central aortic pressure is marred by a lack of data on this parameter compared to the peripheral blood pressure (BP), whatever limited data is there, there is a clear trend that central aortic pressure does predict cardiovascular disease and events better than the peripheral BP. 26) Further, a meta-analysis of 13 randomized controlled trials on hypertension showed that beta blockers were associated with a 16% increased risk of stroke compared to CCBs and ARBs with no difference in MI.

As previously stated, we encourage initiating treatment first with cautious use of NSAIDs and avoidance of IVIG and/or corticosteroids in patients with pediatric post‐vaccine myocarditis who are demonstrating a clear trend towards clinical improvement within 48 hours after presentation (or after initiation of NSAIDs treatment).

There is a clear trend toward universal testing of newly diagnosed colorectal cancers for evidence of microsatellite instability.

After adjusting for confounders, a clear trend was observed for HDL-C, with mean levels decreasing as the number of teeth decreased [ 23 ].

Its purpose is to arrange elements so that those with similar behaviors are placed consecutively. Similar to the previous feature, a clear trend is apparent, wherein a lower mean Mendeleev number among elements in the composition correlates with higher values of E g , with a correlation of ca. −0.53.

The results showed that there was no statistically significant difference in the incidence of MI after the onset between the RAO group and the control group, but there was a clear trend [RR = 1.38, 95% CI (0.80, 2.40)] (Fig. 2 B).

In particular, there is a clear trend for the presence of polar compounds with m / z > 300 and of non-polar compounds with m / z > 400 in leaves.

A clear trend is visible when comparing the middle column with the other two.

No significant differences in average contact number and contact duration were observed between provinces, the number of recorded contacts did not show a clear trend by age, and most of the recorded contacts occurred with family members (about 78%).

However, such an extrapolation can only be done if sufficient degradation has occurred and a clear trend for each stereoisomer is observed.

While other authors have reported no significant association between obesity and neutrophilic airway inflammation, they do illustrate a clear trend of increasing %neutrophils as BMI category increases [ 25 - 27 ].

The opposite trend was observed for lactate, while the level of ethanolamine and serine did not follow a clear trend.

A clear trend of increased yields due to earlier sowing was observed within most states (Fig. 3A ) across the 10 years of the study.

Although the opinion about the need to treat varies greatly among uveitis experts, there seems to exist a generally accepted first choice treatment in the aforementioned surveys: the combination of pyrimethamine and sulfadiazine (PY/SA) with or without systemic corticosteroids seems to represent today’s gold standard for treating systemic as well as OT, whereas there exists a clear trend away from this side-effect-affected combination therapy to the fixed combination therapy with trimethoprim 160 mg and sulfamethoxazole 800 mg (TMP/SMZ) [ 34 ], which demonstrates a similar clinical effect as PY/SA, but has—in the absence of a sulfonamide allergy—an excellent safety profile [ 63 ].

In addition, a clear trend could be seen where aggregates were more compact and roundly shaped as the percentage of BTA-PEG-BTA increased (after 24 hours).

For pre-term deliveries, the graphs in Figures 1 and 2 show a clear trend of a negative relationship between the timing of the introduction of Doppler ultrasound and the decline in fetal deaths.

3(b) ), and showed a clear trend with respect to the alkane length at 3% FGC.

In contrast to Nap, the degradation behavior of Phe in soil containing TiO2-NPs displayed a clear trend.

Among patients with complete or partial remission on 18 FDG-PET-CT, 5 out of 6 showed a measurable decrease in global or focal T2 of more than 2 ms, while in 3 patients with unchanged 18 FDG-PET-CT activity, T2 values behaved inconsistently and did not indicate a clear trend.

While filopodia density was not significantly altered, there was a clear trend toward TTX treatment increasing filopodia in a dose/time-dependent manner ( Figure 2Cii ).

When observing the relative proportion of contacts in each quintile to standardise for differences in total contact count, a clear trend was seen to higher activity early and late in admissions (Fig. 2 B).

Several studies have explored the potential use of α -syn as a PD diagnostic biomarker in human CSF, but the results are inconsistent: some studies have shown a clear trend of lower total CSF α -syn in PD and other types of Parkinsonism such as MSA, DLB, and PSP, whereas others show no significant variation.

There was a clear trend between the presence of a PCR band and the number of sequencing reads, with 9% of samples containing 300–500 reads having a band vs. 71% of samples with 1000–5000 and 91% of samples with more than 5000 reads (Fig. 1 a).

It is worth noting that the original test set may correspond to a relatively “calm” period or one characterized by a clear trend, whereas the block bootstrap procedure simulates a wide range of more challenging fluctuation patterns.

Therefore, at present there is a clear trend for the development and characterization of NHP (macaque) models reproducing the progressive dopaminergic neuronal degeneration as a result of αSyn aggregation.