“a clear trend”

The difference between the two SCI groups showed a clear trend for higher mast cell number with manual expression (unpaired t -test, two-tailed, p = 0.064). 4.

transfer of Tregs into the hypothalamus supported a clear trend towards improved glucose tolerance ( P = 0.0643, Fig. 9g ) accompanied by trends toward reduced inflammatory NFκB-related genes in the adipose tissue (Supplementary Fig. 9e ).

Moreover, according to the Kaplan-Meier analysis, patients who received adequate antiviral treatment demonstrated a clear trend towards reduced complications, although the log-rank p -value was not statistically significant ( p = 0.065) (Fig. 1 ).

Importantly, anti-PD-1 monotherapy produced a clear trend towards reduced M2 macrophages overall, while failing to reach significance when compared to MOPC21 ( P = 0.0654).

Figure 4 demonstrates that compared to the DM group, there was a clear trend towards the inhibition of the expression and phosphorylation of AMPKα in the MICT group ( P =0.066, P =0.056).

2 ), which was significant ( p = 0.04) In the entire cohort the decrease in ATP, although showing a clear trend, did not reach statistical significance ( p = 0.066), whereas ICD shocks did decrease significantly ( p = 0.028).

The difference in distant lymph node metastasis between SARIFA-positive and SARIFA-negative groups showed a clear trend and just failed to show statistical significance ( p = 0.066).

22 In line with previous data, 23 , 24 we observed decreased total IgE (mean −0.47 fold from baseline, ∗∗ p < 0.01) (Figure 5B ) and specific IgE (Der p1) (mean −0.40 fold from baseline, ∗ p < 0.05) (Figure 5C ) while House Dust Mite (HDM) Der p2‐specific IgE (Figure S1f ) showed a clear trend but did not reach statistical significance ( p = 0.0665).

Although the long-term survival rates suggest a clear trend, with a 3-year survival rate of 12.5 % in the CK7+ group and 75 % in the CK7− group ( p -value = 0.067), the difference is not statistically significant.

27 In our study, HBEA was not associated with higher AF detection in the second Holter‐ECG compared with those with NSR, although a clear trend was observed at the 12‐month follow‐up (26% versus 13%, P =0.068).

Although not reaching statistical levels by 2-way ANOVA (interaction p = 0.10) a clear trend for reduced T3/T4 levels was found in HFS ad lib group compared to NC controls ( p = 0.068) and to HFS TRF ( p = 0.055), comforting the idea of local hypothyroidism ( Figure 6 B).

Interestingly, there was a clear trend suggesting that patients with T-ALL harboring a BCL11B mutation had a higher percentage of CR ( P = .068) and negative MRD ( P = .050), although the data were not yet statistically significant at this point ( Figure 1B ).

When the correlation was separately performed for seen and unseen trials, we found that although not statistically significant, there was a clear trend for a correlation between Target presence decoding accuracy and performance in the tilt discrimination task for seen trials ( r = .36, p = .07), but not for unseen trials ( r = − .14, p = .50) (Fig. 9 B and C).

mRNA levels of mTOR were notably reduced in the RAPA and MVC/RAPA groups (p<0.01 and p<0.05, respectively), and there was a clear trend in the MVC group (p = 0.07) ( Fig 2 ).

Mean spike frequency averaged over a 24 h period showed a clear trend towards increased number of spikes in the J20 and Gria2 G/G /J20 mice, though this was not statistically significant (ANOVA; F (3,15) = 2.9 p = 0.07; Fig. 3 b).

In compatible, a clear trend of reduction in transition times normalised to the self-control ( P = 0.0708, Fig. 3 C) was observed in the UMB group (0.4574 ± 0.1173, n = 11) compared to that in the control group (0.8931 ± 0.1690, n = 9).

Although the specified significance threshold was not reached, there was a clear trend toward an improved predictive discrimination of the hybridized ML model with respect to the expert-based model in the test data (Concordance index, P value = .076; AUROC, P value = .731), while a significant difference was patent between the hybridized ML model and the calcium score-based model (Concordance index, P value = .014; AUROC, P value = .025).

Although no statistically significant differences were found in the analysis of survival and antibiotic exposure, there was a clear trend toward longer survival in patients who did not require antibiotic treatment (mOS 23 months for non-use vs 12 months for use of antibiotics; p = 0.078).

A clear trend towards a higher mortality was noted in the older population (72.9% vs. 56.6%; p=0.078).

Global longitudinal strain showed a clear trend towards its reduction in patients with CA (−12 ± 5.5% vs. −19 ± 0.6%; p = 0.078), although differences were not statistically significant.

In the group receiving IST, there was a clear trend towards lower mortality (23.8 vs. 53.8, p = 0.080) and a significant improvement in LVEF (29.8 ± 11.7 → 35.9 ± 13.9, p = 0.036 vs. 26.5 ± 11.9 → 33.6 ± 14.2, p = 0.208) compared to DCM patients with myocarditis who did not receive IST.

Moreover, although the statistical analysis did not show any significant differences between the treatment groups and the PBS + VEH group, a clear trend toward increasing the absolute number of ST2 + CD4 + T cells in the lungs of mice treated with MMF ( p = 0.080) and TFB ( p = 0.107) can be observed ( Figure 5 D).

Although there was a clear trend towards benefit in the experimental arm, this difference was not statistically significant ( p = 0.08).

Impact of IV-ATV on Cardiac Innate Immune Cell Infiltration DCM-vehicle animals showed a clear trend ( P = 0.08) toward a higher (40%) neutrophil infiltration and a significant increase in macrophage content in the infarcted heart compared with NC-vehicle rats ( Fig. 7 A and B ).

Although the effect was not statistically significant, there was a clear trend for DXM to reduce the number of infiltrating T-lymphocytes, particularly CD8 + T-cells (p=0.08).