“a decreasing trend”

In the gender subgroups, there was a decreasing trend in bone mineral density levels for both men [-0.017 (-0.026, -0.008), p = 0.001] and women [-0.012 (-0.024, -0.001), p < 0.074].

By age group, there was a statistically significant increasing trend in the groups of patients aged 19 years or younger (p<0.001) and 20–29 years (p<0.001), and a decreasing trend in the groups of patients aged 30–39 years (p=0.001), 40–49 years (p<0.001) and 60–69 years (p=0.017).

Combination therapy was the predominant pattern of treatment, monotherapy showed a decreasing trend over time ( p < 0.001), while the proportion of dual combination therapy and triple or more combination therapy kept on increasing during the 5-year period (both p < 0.001).

The seven-year PV of Clostridium butyricum , Bacillus mesentericus , and Enterococcus faecalis was 10.9% with a decreasing trend (Z = -4.40, p < 0.001).

7 The incidence of ICC among Japanese women aged 20–29 years significantly increased during 1975–2011 (APC 5.9, 95% confidence interval [95%CI] 5.6 to 6.1, p < 0.001), in line with previous reports, 13 , 14 , 15 but converted to a decreasing trend from 8.0 to 2.8 (reduction rate 65.0%) during 2011–2020 (APC −13.5, 95%CI −11.9 to −14.5, p < 0.001).

Of note, these failure rates show a decreasing trend year by year in both self-check and cross-check ( χ 2 = 1476.114, P < 0.001, χ 2 = 1098.832, P < 0.001, χ 2 = 86.565, P < 0.001, χ 2 = 50.620, P < 0.001, respectively).

In the Northeast, only São Luís - MA showed a decreasing trend (AAPC = -4.6%; 95%CI -6.8 to -2.4; p = 0.001) (Table 3 ).

However, the umbilical cord serum to maternal serum 25(OH)D ratio showed a decreasing trend with maternal serum levels ( P < .001).

Conversely, the homicide rate had a decreasing trend before the pandemic, with a significant monthly decrease of 2.8% (IRR = 0.982; P = 0.001).

The data indicated a significant increasing trend in the prevalence of DM, from 8.3% (in 2009) to 9.7% (in 2019) (p=0.004), in contrast the prevalence of CVD among patients with DM showed a decreasing trend (from 33.9% to 20.4%; p<0.001).

The FI, MNA-SF score and the prevalence of hypertension, diabetes, dyslipidemia, comorbidities and polypharmacy, as well as the levels of SBP, DBP, BMI, waist circumference, uric acid, TG, TC, LDL-C, FPG, HbA1c and albumin, exhibited an increasing trend with the elevated TyG index, except for the levels of HDL-C which showed a decreasing trend (all P < 0.001).

Additionally, there was a decreasing trend in female proportion as early WBS neck counts increased ( p < 0.001).

Joinpoint regression analysis showed an increasing trend from January to May for the whole population (APC = 22.7%, 95% CI: 8.2–39.2%, P = 0.006) and a decreasing trend from May to December (APC = -19.1%, 95% CI: -23.3% ~-14.7%, P < 0.001).

The total detection rate of newly diagnosed patients with echinococcosis, as well as that of CE and AE, demonstrated a decreasing trend year by year ( χ 2 = 1,054.785, 925.936, 196.018; P < 0.001).

1 A,B; the APC for each subgroup is presented in Table S2 ), except a decreasing trend of incidence in unknown receptor subtype subgroup (32.55 to 12.61 per 100,000 women from 2010 to 2019; APC: − 8.6, 95% CI − 11.1 to − 6.1, P < 0.001).

As a result, a decreasing trend of HVPG was observed with a more distal catheter position in the hepatic vein during pressure measurement ( p < 0.001) (Fig. 3 e).

Each of the study outcomes had a decreasing trend across the study period (ordinary least square P -value <.001).

Thus, there was a decreasing trend in the number of CLCC posts over time (slope = −31.6; intercept = 6030.0; p -value < 0.001), with notable small spikes around 20 April (or “4/20” in the U.S.)—a date associated with cannabis culture that appears to drive cross-promotion of tobacco products—every year during the period of observation ( Figure 1 ).

Additionally, the average intracranial pressure (ICP) demonstrated a significant increase with higher class levels ( p < 0.001), while CT values exhibited a decreasing trend ( p < 0.001).

Temporal trends of unintentional injury mortality by age groups In the 0–4 age group, the unintentional injury mortality rate had a decreasing trend in males (AAPC=–4.6%, p<0.001) and females (AAPC=–6.8%, p<0.001).

For instance, the estimates for the first cluster (intercept = 2330.26, slope = -128.2) reveal that the initial rate of urolithiasis in the countries including this cluster, Afghanistan, Andorra, and Comoros, has been 2330.26 per 100000 in 1990, and it has a decreasing trend with a slope of -128.2 until 2019, every two years ( P -value < 0.001).

Conversely, body mass index (BMI), the proportion of patients with primary infertility, the proportion of blastocyst transfers, and the proportion of first IVF-FET cycles exhibited a decreasing trend (all P < 0.001).

A decreasing trend was seen in the number of clients with low mental well-being across the three follow-up moments (p<0.001), with a significant difference between preintervention and 2 mo postintervention (p<0.001).

While GSH-Px showed a decreasing trend ( P < 0.001) as the transport duration increased (1.44 vs. 1.21 vs. 0.06 vs. 0.04 μmol/mg Hb for T1, T2, T3, and T4, respectively).

These results were consistent with the findings from Western blotting.Similarly, IHC analysis demonstrated a significant increase in p62 expression from 1 week to 2 weeks of age ( p < 0.001), peaking at 2 weeks of age, and then exhibiting a decreasing trend from 2 weeks to 8 weeks of age ( p < 0.001) ( Figure 5 D).