Although the stance/swing ratio of the Ex group and Gs group also showed a decreasing trend, it was not statistically significant (P = 0.1322 and P = 0.0572, respectively), indicating limited gait improvement.
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The FCM analysis indicated that DKK1 inhibition induced significantly higher infiltration of NK cells and lower infiltration of M2 macrophages in the tumors (Figure S1C,D ), and a decreasing trend of M2 macrophage infiltration in the spleens ( p = 0.1339; Figure S1G ).
The full conversion rate showed a decreasing trend from 7.3 to 2.4% ( p = 0.134).
S8a and b ), even for the highly resistant GTR0455 cells that showed a decreasing trend (P = 0.138) (Figs. 4c and S9 ).
The differences in the mean escape latency between day 1 and day 3 in the Y-TWK10 group showed a decreasing trend ( P = 0.1388) compared to the Y-Control mice ( Figure 2B ) whereas those in the A-TWK10 group were significantly lower ( P < 0.05) than those in the A-Control group ( Figure 2C ).
Compared with that in the clopidogrel + IR group, the tail bleeding time showed a decreasing trend in the TMAO + clopidogrel + IR group (10.5 min ± 8.63 min, P = 0.139) (Fig. 2 ).
The overall pooled effect estimate was 0.58 (95% CI, 0.40–0.83). Effectiveness of Prophylactic Anti-VEGF in Preserving Vision Although there was a decreasing trend in moderate vision loss favoring the control group, the difference was not significant (pooled OR, 0.12; 95% CI, 0.01–1.97; p = 0.139) ( Figure 4 ).
The difference in change in BMI z-score over-time between INT and COMP was not statistically significant (− 0.08, 95%CI -0.24 – 0.08, p = 0.31). Change in HRQoL A decreasing trend on CHU9D utilities was observed for both INT (0.804 baseline, 0.792 final; adjusted difference = − 0.012, p = 0.139) and COMP (0.820 baseline, 0.766 final; adjusted difference = − 0.054, p < 0.001).
VEGF expression presented a decreasing trend in group ME compared to E ( p = 0.14).
(3) Results: The PE group had significant reductions in wrinkle severity ( p < 0.01) and a decreasing trend in the forehead sebum excretion rate ( p = 0.14).
Similarly, a decreasing trend was observed in SampEn estimated from SSI, dP1, or dP2 ( p = 0.14), while the change of RRI SampEn was far from the statistical significance ( p = 0.50).
A decreasing trend in the microbial diversity and richness was observed in patients after ART ( Figure S1A , Fisher P = 0.14, Chao1 P = 0.16, ACE P = 0.16, Shannon P = 0.16).
However, there was a decreasing trend of WGR in the MBP12 group in comparison with that of the MBP0 group ( p = 0.14). 3.2.
The levels of other adipokines, including adiponectin, leptin, and plasminogen activator inhibitor-1 (PAI-1) in the adipocytes were similar between the groups, although, a decreasing trend was observed in the levels of adiponectin ( p = 0.14, 6 mice each, Supplementary Data 1 ).
We also found a decreasing trend in PAD provision rates during the pandemic only in high-burden regions (pandemic vs. pre-pandemic period: 8.4% vs. 10.0%; cOR, 95% CI: 0.83, 0.64-1.06; P=0.14), with an increasing trend in low-burden regions (8.1% vs. 7.3%; cOR, 95% CI: 1.12, 0.98-1.29; P=0.10) (interaction P=0.03).
At the 3-month time point, the dopamine levels in the striatum of the anti-IgLON5 antibody-injected mice still showed a decreasing trend compared to the control group ( n = 5, p = 0.143).
CON, respectively), and MH-treated mice showed a decreasing trend in the levels of p-p70S6K at 30 min after KA-treated hippocampus ( Fig. 3B ; p=0.144).
There were no differences in the Npr1 / Npr3 ratio between untreated HFpEF and Sham mice; however, this ratio was significantly increased by 43% in the soleus muscle of musclin-treated versus untreated HFpEF mice ( P =0.027; Figure 3 E), driven mainly by a decreasing trend in Npr3 gene expression in musclin-treated HFpEF mice ( P =0.146; Figure S3 ), suggesting that exogenous musclin increased NP signaling activity.
Despite a decreasing trend in the markers of bone metabolism including N-MID (13.80 ± 3.23 vs. 12.85 ± 3.69 vs. 11.31 ± 4.24 ng/mL, p = 0.148), PINP (37.12 ± 8.38 vs. 34.45 ± 9.91 vs. 30.87 ± 8.41 ng/mL, p = 0.142), and 25-hydroxyvitamin D (27.72 ± 13.67 vs. 24.37 ± 7.52 vs. 21.96 ± 8.90 ng/mL, p = 0.177) in the osteopenia and osteoporosis groups at baseline, there was no statistically significant difference between the groups.
However, serum OXT levels were notably lower in the C57-SI group ( P < 0.05), and a decreasing trend was observed in PFC OXT levels ( P = 0.15, Fig. 3B ).
Mocetinostat showed a decreasing trend in the level of STAT3 protein in LV of treated CHF compared to untreated CHF animals ( p = 0.15).
The results showed a significant decrease in the DNA methylation of ESRRA (FC = 0.6, p = 0.0096) and EGFR (FC = 0.5, p = 0.038) and a decreasing trend in ARID2 (FC = 0.7, p = 0.15) and SUV39H1 (FC = 0.63, p = 0.13) in the high BPA group compared to the low BPA group (Fig. 1 C).
Conversely, the SMR among women displayed a decreasing trend averaging 0.50 cases per year per 100,000 residents also failing to reach significance ( p = 0.15).
In the first session, similar to that observed for subjects in the short-term study, VOR responses showed a decreasing trend for HR peak eye velocity and an increasing trend for LR peak eye velocity (Figure 2A ), the changes were not significant for HR (35.0 ± 3.6 vs. 26.0 ± 4.4°/s, paired t -test, p = 0.15) or LR (25.0 ± 2.2 vs. 26.75 ± 5.3°/s, paired t -test, p = 0.23).
Notably, total serum RNA level had a decreasing trend in the S-R group at day 3 ( P = 0.15) and day 7 ( P = 0.09) postoperatively (n = 5) ( Fig 3 ).